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SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion.
Fan, Xueping; Yang, Hongying; Kumar, Sudhir; Tumelty, Kathleen E; Pisarek-Horowitz, Anna; Rasouly, Hila Milo; Sharma, Richa; Chan, Stefanie; Tyminski, Edyta; Shamashkin, Michael; Belghasem, Mostafa; Henderson, Joel M; Coyle, Anthony J; Salant, David J; Berasi, Stephen P; Lu, Weining.
Afiliación
  • Fan X; Renal Section, Department of Medicine, Boston University Medical Center, Boston, Massachusetts, USA.
  • Yang H; Centers for Therapeutic Innovation, Pfizer Inc., Boston, Massachusetts, USA.
  • Kumar S; Renal Section, Department of Medicine, Boston University Medical Center, Boston, Massachusetts, USA.
  • Tumelty KE; Centers for Therapeutic Innovation, Pfizer Inc., Boston, Massachusetts, USA.
  • Pisarek-Horowitz A; Renal Section, Department of Medicine, Boston University Medical Center, Boston, Massachusetts, USA.
  • Rasouly HM; Renal Section, Department of Medicine, Boston University Medical Center, Boston, Massachusetts, USA.
  • Sharma R; Renal Section, Department of Medicine, Boston University Medical Center, Boston, Massachusetts, USA.
  • Chan S; Renal Section, Department of Medicine, Boston University Medical Center, Boston, Massachusetts, USA.
  • Tyminski E; Centers for Therapeutic Innovation, Pfizer Inc., Boston, Massachusetts, USA.
  • Shamashkin M; Centers for Therapeutic Innovation, Pfizer Inc., Boston, Massachusetts, USA.
  • Belghasem M; Department of Pathology and Laboratory Medicine, Boston University Medical Center, Boston, Massachusetts, USA.
  • Henderson JM; Department of Pathology and Laboratory Medicine, Boston University Medical Center, Boston, Massachusetts, USA.
  • Coyle AJ; Centers for Therapeutic Innovation, Pfizer Inc., Boston, Massachusetts, USA.
  • Salant DJ; Renal Section, Department of Medicine, Boston University Medical Center, Boston, Massachusetts, USA.
  • Berasi SP; Centers for Therapeutic Innovation, Pfizer Inc., Boston, Massachusetts, USA.
  • Lu W; Renal Section, Department of Medicine, Boston University Medical Center, Boston, Massachusetts, USA.
JCI Insight ; 1(19): e86934, 2016 Nov 17.
Article en En | MEDLINE | ID: mdl-27882344
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores Inmunológicos / Transducción de Señal / Proteínas Activadoras de GTPasa / Miosina Tipo IIA no Muscular / Péptidos y Proteínas de Señalización Intercelular / Podocitos / Proteínas del Tejido Nervioso Tipo de estudio: Guideline / Prognostic_studies Límite: Animals Idioma: En Revista: JCI Insight Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores Inmunológicos / Transducción de Señal / Proteínas Activadoras de GTPasa / Miosina Tipo IIA no Muscular / Péptidos y Proteínas de Señalización Intercelular / Podocitos / Proteínas del Tejido Nervioso Tipo de estudio: Guideline / Prognostic_studies Límite: Animals Idioma: En Revista: JCI Insight Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos