Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to Stabilize the High Affinity State under Force.

Mehta-D'souza, Padmaja; Klopocki, Arkadiusz G; Oganesyan, Vaheh; Terzyan, Simon; Mather, Timothy; Li, Zhenhai; Panicker, Sumith R; Zhu, Cheng; McEver, Rodger P

Mehta-D'souza, Padmaja; Klopocki, Arkadiusz G; Oganesyan, Vaheh; Terzyan, Simon; Mather, Timothy; Li, Zhenhai; Panicker, Sumith R; Zhu, Cheng; McEver, Rodger P.

Afiliación

Mehta-D'souza P; From the Cardiovascular Biology Research Program and.
Klopocki AG; From the Cardiovascular Biology Research Program and.
Oganesyan V; From the Cardiovascular Biology Research Program and.
Terzyan S; Crystallography Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma 73104.
Mather T; From the Cardiovascular Biology Research Program and.
Li Z; the Coulter Department of Biomedical Engineering.
Panicker SR; From the Cardiovascular Biology Research Program and.
Zhu C; the Coulter Department of Biomedical Engineering.
McEver RP; Woodruff School of Mechanical Engineering, and.

J Biol Chem ; 292(6): 2510-2518, 2017 02 10.

Article en En | MEDLINE | ID: mdl-28011641

Asunto(s)

Ácido Glutámico/metabolismo; Selectina L/metabolismo; Polisacáridos/metabolismo; Animales; Células CHO; Cricetinae; Cricetulus; Cristalografía por Rayos X; Humanos; Selectina L/química; Glicoproteínas de Membrana/metabolismo; Conformación Proteica

Palabras clave

carbohydrate-binding protein; cell adhesion; endothelial cell; glycobiology; inflammation; leukocyte

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Polisacáridos / Ácido Glutámico / Selectina L Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2017 Tipo del documento: Article

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