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A mitochondria-targeting fluorescent probe for the selective detection of glutathione in living cells.
Liu, Xue-Liang; Niu, Li-Ya; Chen, Yu-Zhe; Zheng, Mei-Ling; Yang, Yunxu; Yang, Qing-Zheng.
Afiliación
  • Liu XL; School of Chemistry and biological Engineering, University of Science and Technology Beijing, Beijing 100083, P. R. China. yxyang@ustb.edu.cn.
  • Niu LY; Key Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, P. R. China. niuly@bnu.edu.cn qzyang@bnu.edu.cn.
  • Chen YZ; Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.
  • Zheng ML; Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.
  • Yang Y; School of Chemistry and biological Engineering, University of Science and Technology Beijing, Beijing 100083, P. R. China. yxyang@ustb.edu.cn.
  • Yang QZ; Key Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, P. R. China. niuly@bnu.edu.cn qzyang@bnu.edu.cn.
Org Biomol Chem ; 15(5): 1072-1075, 2017 Feb 01.
Article en En | MEDLINE | ID: mdl-28059419
We report a fluorescent probe for the selective detection of mitochondrial glutathione (GSH). The probe, containing triphenylphosphine as a mitochondrial targeting group, exhibited ratiometric and selective detection of GSH over Cys/Hcy. The probe was used for imaging mitochondrial GSH in living HeLa cells.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Colorantes Fluorescentes / Glutatión / Mitocondrias Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Org Biomol Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2017 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Colorantes Fluorescentes / Glutatión / Mitocondrias Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Org Biomol Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2017 Tipo del documento: Article