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Progranulin regulates lysosomal function and biogenesis through acidification of lysosomes.
Tanaka, Yoshinori; Suzuki, Genjiro; Matsuwaki, Takashi; Hosokawa, Masato; Serrano, Geidy; Beach, Thomas G; Yamanouchi, Keitaro; Hasegawa, Masato; Nishihara, Masugi.
Afiliación
  • Tanaka Y; Department of Dementia and Higher Brain function, Dementia Research Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan.
  • Suzuki G; Department of Veterinary Physiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.
  • Matsuwaki T; Department of Dementia and Higher Brain function, Dementia Research Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan.
  • Hosokawa M; Department of Veterinary Physiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.
  • Serrano G; Department of Dementia and Higher Brain function, Dementia Research Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan.
  • Beach TG; Civin Laboratory for Neuropathology, Banner Sun Health Research Institute, 10515 West Santa Fe Drive, Sun City AZ 85351, USA.
  • Yamanouchi K; Civin Laboratory for Neuropathology, Banner Sun Health Research Institute, 10515 West Santa Fe Drive, Sun City AZ 85351, USA.
  • Hasegawa M; Department of Veterinary Physiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.
  • Nishihara M; Department of Dementia and Higher Brain function, Dementia Research Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan.
Hum Mol Genet ; 26(5): 969-988, 2017 03 01.
Article en En | MEDLINE | ID: mdl-28073925
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Catepsina D / Péptidos y Proteínas de Señalización Intercelular / Proteínas de Unión al ADN / Degeneración Lobar Frontotemporal / Neuronas Límite: Animals / Humans Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2017 Tipo del documento: Article País de afiliación: Japón
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Catepsina D / Péptidos y Proteínas de Señalización Intercelular / Proteínas de Unión al ADN / Degeneración Lobar Frontotemporal / Neuronas Límite: Animals / Humans Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2017 Tipo del documento: Article País de afiliación: Japón