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Engineering the ribosomal DNA in a megabase synthetic chromosome.
Zhang, Weimin; Zhao, Guanghou; Luo, Zhouqing; Lin, Yicong; Wang, Lihui; Guo, Yakun; Wang, Ann; Jiang, Shuangying; Jiang, Qingwen; Gong, Jianhui; Wang, Yun; Hou, Sha; Huang, Jing; Li, Tianyi; Qin, Yiran; Dong, Junkai; Qin, Qin; Zhang, Jiaying; Zou, Xinzhi; He, Xi; Zhao, Li; Xiao, Yibo; Xu, Meng; Cheng, Erchao; Huang, Ning; Zhou, Tong; Shen, Yue; Walker, Roy; Luo, Yisha; Kuang, Zheng; Mitchell, Leslie A; Yang, Kun; Richardson, Sarah M; Wu, Yi; Li, Bing-Zhi; Yuan, Ying-Jin; Yang, Huanming; Lin, Jiwei; Chen, Guo-Qiang; Wu, Qingyu; Bader, Joel S; Cai, Yizhi; Boeke, Jef D; Dai, Junbiao.
Afiliación
  • Zhang W; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Zhao G; Tsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China.
  • Luo Z; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Lin Y; Peking University-Tsinghua University-National Institute of Biological Sciences Joint Graduate Program, College of Life Science, Peking University, Beijing 100871, China.
  • Wang L; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Guo Y; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Wang A; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Jiang S; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Jiang Q; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Gong J; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Wang Y; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Hou S; BGI-Shenzhen, Shenzhen 518083, China.
  • Huang J; BGI-Shenzhen, Shenzhen 518083, China.
  • Li T; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Qin Y; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Dong J; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Qin Q; Tsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China.
  • Zhang J; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Zou X; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • He X; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Zhao L; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Xiao Y; Tsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China.
  • Xu M; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Cheng E; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Huang N; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Zhou T; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Shen Y; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Walker R; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Luo Y; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Kuang Z; Key Laboratory for Industrial Biocatalysis (Ministry of Education) and Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Mitchell LA; BGI-Shenzhen, Shenzhen 518083, China.
  • Yang K; School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3BF, UK.
  • Richardson SM; BGI-Qingdao, Qingdao 266555, China.
  • Wu Y; School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3BF, UK.
  • Li BZ; School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3BF, UK.
  • Yuan YJ; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, New York University Langone Medical Center, New York, NY 10011, USA.
  • Yang H; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, New York University Langone Medical Center, New York, NY 10011, USA.
  • Lin J; High-Throughput Biological Center and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Chen GQ; High-Throughput Biological Center and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Wu Q; Key Laboratory of Systems Bioengineering (Ministry of Education), SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
  • Bader JS; Key Laboratory of Systems Bioengineering (Ministry of Education), SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
  • Cai Y; Key Laboratory of Systems Bioengineering (Ministry of Education), SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
  • Boeke JD; BGI-Shenzhen, Shenzhen 518083, China.
  • Dai J; James D. Watson Institute of Genome Sciences, Hangzhou 310058, China.
Science ; 355(6329)2017 03 10.
Article en En | MEDLINE | ID: mdl-28280149
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Saccharomyces cerevisiae / ADN Ribosómico / Ingeniería Genética / Genoma Fúngico / Cromosomas Artificiales de Levadura / Biología Sintética Idioma: En Revista: Science Año: 2017 Tipo del documento: Article País de afiliación: China
Texto completo
Imprimir
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Saccharomyces cerevisiae / ADN Ribosómico / Ingeniería Genética / Genoma Fúngico / Cromosomas Artificiales de Levadura / Biología Sintética Idioma: En Revista: Science Año: 2017 Tipo del documento: Article País de afiliación: China