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SPR-based fragment screening with neurotensin receptor 1 generates novel small molecule ligands.
Huber, Sylwia; Casagrande, Fabio; Hug, Melanie N; Wang, Lisha; Heine, Philipp; Kummer, Lutz; Plückthun, Andreas; Hennig, Michael.
Afiliación
  • Huber S; Roche Innovation Center Basel, Pharmaceutical Research and Early Development, Basel, Switzerland.
  • Casagrande F; Roche Innovation Center Basel, Pharmaceutical Research and Early Development, Basel, Switzerland.
  • Hug MN; Roche Innovation Center Basel, Pharmaceutical Research and Early Development, Basel, Switzerland.
  • Wang L; Roche Innovation Center Basel, Pharmaceutical Research and Early Development, Basel, Switzerland.
  • Heine P; Department of Biochemistry, University of Zurich, Zurich, Switzerland.
  • Kummer L; Department of Biochemistry, University of Zurich, Zurich, Switzerland.
  • Plückthun A; Department of Biochemistry, University of Zurich, Zurich, Switzerland.
  • Hennig M; Roche Innovation Center Basel, Pharmaceutical Research and Early Development, Basel, Switzerland.
PLoS One ; 12(5): e0175842, 2017.
Article en En | MEDLINE | ID: mdl-28510609
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores de Neurotensina / Bibliotecas de Moléculas Pequeñas / Descubrimiento de Drogas Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2017 Tipo del documento: Article País de afiliación: Suiza
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores de Neurotensina / Bibliotecas de Moléculas Pequeñas / Descubrimiento de Drogas Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2017 Tipo del documento: Article País de afiliación: Suiza