Binding assay for characterization of protein kinase inhibitors possessing sub-picomolar to sub-millimolar affinity.

Sinijarv, Hedi; Wu, Shanshan; Ivan, Taavi; Laasfeld, Tonis; Viht, Kaido; Uri, Asko

Sinijarv, Hedi; Wu, Shanshan; Ivan, Taavi; Laasfeld, Tonis; Viht, Kaido; Uri, Asko.

Afiliación

Sinijarv H; Institute of Chemistry, University of Tartu, 14A Ravila St., 50411 Tartu, Estonia.
Wu S; Institute of Chemistry, University of Tartu, 14A Ravila St., 50411 Tartu, Estonia.
Ivan T; Institute of Chemistry, University of Tartu, 14A Ravila St., 50411 Tartu, Estonia.
Laasfeld T; Institute of Chemistry, University of Tartu, 14A Ravila St., 50411 Tartu, Estonia. Electronic address: tonis.laasfeld@gmail.com.
Viht K; Institute of Chemistry, University of Tartu, 14A Ravila St., 50411 Tartu, Estonia.
Uri A; Institute of Chemistry, University of Tartu, 14A Ravila St., 50411 Tartu, Estonia. Electronic address: asko.uri@ut.ee.

Anal Biochem ; 531: 67-77, 2017 08 15.

Article en En | MEDLINE | ID: mdl-28527909

Asunto(s)

Técnicas Biosensibles/métodos; Proteínas Quinasas Dependientes de AMP Cíclico/química; Fluorescencia; Inhibidores de Proteínas Quinasas/análisis; Humanos; Inhibidores de Proteínas Quinasas/química

Palabras clave

Affinity; Cheng-Prusoff equation; Control chart; Photoluminescence; Protein kinase inhibitor; Time-gated measurement

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Técnicas Biosensibles / Proteínas Quinasas Dependientes de AMP Cíclico / Inhibidores de Proteínas Quinasas / Fluorescencia Límite: Humans Idioma: En Revista: Anal Biochem Año: 2017 Tipo del documento: Article País de afiliación: Estonia

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google