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C21 steroidal glycosides from Cynanchum taihangense.
Wang, Yu-Bo; Su, Shan-Shan; Chen, Shao-Fei; Tang, Ming-Xu; Chen, Gang; Zhao, Dan; Sang, Xia-Nan; Si, Ying-Ying; Wang, Hai-Feng; Pei, Yue-Hu.
Afiliación
  • Wang YB; a School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University , Shenyang 110016 , China.
  • Su SS; b Key Laboratory of Structure-Based Drug Design and Discovery , Ministry of Education, Shenyang Pharmaceutical University , Shenyang 110016 , China.
  • Chen SF; c School of Pharmacy, Jinzhou Medical University , Jinzhou 121001 , China.
  • Tang MX; d Testing Laboratory , Qinghai Entry-Exit Inspection and Quarantine Bureau , Xining 810000 , China.
  • Chen G; a School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University , Shenyang 110016 , China.
  • Zhao D; b Key Laboratory of Structure-Based Drug Design and Discovery , Ministry of Education, Shenyang Pharmaceutical University , Shenyang 110016 , China.
  • Sang XN; a School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University , Shenyang 110016 , China.
  • Si YY; b Key Laboratory of Structure-Based Drug Design and Discovery , Ministry of Education, Shenyang Pharmaceutical University , Shenyang 110016 , China.
  • Wang HF; a School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University , Shenyang 110016 , China.
  • Pei YH; b Key Laboratory of Structure-Based Drug Design and Discovery , Ministry of Education, Shenyang Pharmaceutical University , Shenyang 110016 , China.
J Asian Nat Prod Res ; 20(3): 263-269, 2018 Mar.
Article en En | MEDLINE | ID: mdl-28537086
ABSTRACT
Two new C21 steroidal glycosides, cynataihosides E (1) and F (2), together with a known one, sublanceoside H2 (3), were isolated from Cynanchum taihangense. The aglycone of cynataihoside F (2) was also a new compound. Their structures were elucidated on the basis of NMR spectroscopic data, HR-ESI-MS analysis, and chemical evidence. Their cytotoxic activities against three human tumor cell lines (HL-60, THP1, and Caco2) were reported.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Esteroides / Cynanchum / Glicósidos Límite: Humans Idioma: En Revista: J Asian Nat Prod Res Asunto de la revista: BOTANICA / QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Esteroides / Cynanchum / Glicósidos Límite: Humans Idioma: En Revista: J Asian Nat Prod Res Asunto de la revista: BOTANICA / QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: China