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Phenotypic Identification of a Novel Autophagy Inhibitor Chemotype Targeting Lipid Kinase VPS34.
Robke, Lucas; Laraia, Luca; Carnero Corrales, Marjorie A; Konstantinidis, Georgios; Muroi, Makoto; Richters, André; Winzker, Michael; Engbring, Tobias; Tomassi, Stefano; Watanabe, Nobumoto; Osada, Hiroyuki; Rauh, Daniel; Waldmann, Herbert; Wu, Yao-Wen; Engel, Julian.
Afiliación
  • Robke L; Max-Planck-Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany.
  • Laraia L; Faculty of Chemistry and Chemical Biology, TU Dortmund University, Otto-Hahn-Strasse 4a, 44227, Dortmund, Germany.
  • Carnero Corrales MA; Max-Planck-Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany.
  • Konstantinidis G; Max-Planck-Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany.
  • Muroi M; Faculty of Chemistry and Chemical Biology, TU Dortmund University, Otto-Hahn-Strasse 4a, 44227, Dortmund, Germany.
  • Richters A; Chemical Genomics Centre of the Max-Planck-Society, Otto-Hahn-Strasse 15, 44227, Dortmund, Germany.
  • Winzker M; Chemical Biology Research Group, RIKEN CSRS, 2-1, Hirosawa, Wako, Saitama, 351-0198, Japan.
  • Engbring T; RIKEN-Max Planck Joint Research Division for Systems Chemical Biology, RIKEN CSRS, 2-1, Hirosawa, Wako, Saitama, 351-0198, Japan.
  • Tomassi S; Faculty of Chemistry and Chemical Biology, TU Dortmund University, Otto-Hahn-Strasse 4a, 44227, Dortmund, Germany.
  • Watanabe N; Max-Planck-Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany.
  • Osada H; Faculty of Chemistry and Chemical Biology, TU Dortmund University, Otto-Hahn-Strasse 4a, 44227, Dortmund, Germany.
  • Rauh D; Faculty of Chemistry and Chemical Biology, TU Dortmund University, Otto-Hahn-Strasse 4a, 44227, Dortmund, Germany.
  • Waldmann H; Faculty of Chemistry and Chemical Biology, TU Dortmund University, Otto-Hahn-Strasse 4a, 44227, Dortmund, Germany.
  • Wu YW; RIKEN-Max Planck Joint Research Division for Systems Chemical Biology, RIKEN CSRS, 2-1, Hirosawa, Wako, Saitama, 351-0198, Japan.
  • Engel J; Bio-Active Compounds Discovery Research Unit, RIKEN CSRS, 2-1, Hirosawa, Wako, Saitama, 351-0198, Japan.
Angew Chem Int Ed Engl ; 56(28): 8153-8157, 2017 07 03.
Article en En | MEDLINE | ID: mdl-28544137
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirazoles / Pirimidinas / Autofagia / Inhibidores de Proteínas Quinasas / Fosfatidilinositol 3-Quinasas Clase III Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Angew Chem Int Ed Engl Año: 2017 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirazoles / Pirimidinas / Autofagia / Inhibidores de Proteínas Quinasas / Fosfatidilinositol 3-Quinasas Clase III Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Angew Chem Int Ed Engl Año: 2017 Tipo del documento: Article País de afiliación: Alemania