Monocyte-Derived Dendritic Cells with Silenced PD-1 Ligands and Transpresenting Interleukin-15 Stimulate Strong Tumor-Reactive T-cell Expansion.

Van den Bergh, Johan M J; Smits, Evelien L J M; Berneman, Zwi N; Hutten, Tim J A; De Reu, Hans; Van Tendeloo, Viggo F I; Dolstra, Harry; Lion, Eva; Hobo, Willemijn

Van den Bergh, Johan M J; Smits, Evelien L J M; Berneman, Zwi N; Hutten, Tim J A; De Reu, Hans; Van Tendeloo, Viggo F I; Dolstra, Harry; Lion, Eva; Hobo, Willemijn.

Afiliación

Van den Bergh JMJ; Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium. johan.vandenbergh@uantwerpen.be.
Smits ELJM; Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
Berneman ZN; Center for Oncological Research Antwerp, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
Hutten TJA; Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
De Reu H; Laboratory of Hematology, Department of Laboratory Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.
Van Tendeloo VFI; Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
Dolstra H; Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
Lion E; Laboratory of Hematology, Department of Laboratory Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.
Hobo W; Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.

Cancer Immunol Res ; 5(8): 710-715, 2017 08.

Article en En | MEDLINE | ID: mdl-28637876

Asunto(s)

Vacunas contra el Cáncer/administración & dosificación; Células Dendríticas/trasplante; Interleucina-15/genética; Receptor de Muerte Celular Programada 1/genética; Antígeno B7-H1/genética; Antígeno B7-H1/inmunología; Linfocitos T CD8-positivos/inmunología; Vacunas contra el Cáncer/genética; Vacunas contra el Cáncer/inmunología; Células Dendríticas/inmunología; Efecto Injerto vs Tumor/efectos de los fármacos; Efecto Injerto vs Tumor/inmunología; Humanos; Interleucina-15/antagonistas & inhibidores; Monocitos/inmunología; Monocitos/trasplante; Proteína 2 Ligando de Muerte Celular Programada 1/genética; Proteína 2 Ligando de Muerte Celular Programada 1/inmunología; Receptor de Muerte Celular Programada 1/antagonistas & inhibidores; ARN Interferente Pequeño/genética; Trasplante de Células Madre; Transfección; Trasplante Homólogo; Vacunación

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Dendríticas / Vacunas contra el Cáncer / Interleucina-15 / Receptor de Muerte Celular Programada 1 Límite: Humans Idioma: En Revista: Cancer Immunol Res Año: 2017 Tipo del documento: Article País de afiliación: Bélgica

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