Prenatal Growth Patterns and Birthweight Are Associated With Differential DNA Methylation and Gene Expression of Cardiometabolic Risk Genes in Human Placentas: A Discovery-Based Approach.

Chen, Pao-Yang; Chu, Alison; Liao, Wen-Wei; Rubbi, Liudmilla; Janzen, Carla; Hsu, Fei-Man; Thamotharan, Shanthie; Ganguly, Amit; Lam, Larry; Montoya, Dennis; Pellegrini, Matteo; Devaskar, Sherin U

Chen, Pao-Yang; Chu, Alison; Liao, Wen-Wei; Rubbi, Liudmilla; Janzen, Carla; Hsu, Fei-Man; Thamotharan, Shanthie; Ganguly, Amit; Lam, Larry; Montoya, Dennis; Pellegrini, Matteo; Devaskar, Sherin U.

Afiliación

Chen PY; 1 Institute of Plant and Microbial Biology, Academia Sinica, Taipei, Taiwan.
Chu A; 2 Division of Neonatology and Developmental Biology, Department of Pediatrics, Neonatal Research Center of the UCLA Children's Discovery and Innovation Institute, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Liao WW; 1 Institute of Plant and Microbial Biology, Academia Sinica, Taipei, Taiwan.
Rubbi L; 3 Department of Molecular, Cell, and Developmental Biology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Janzen C; 4 Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Hsu FM; 1 Institute of Plant and Microbial Biology, Academia Sinica, Taipei, Taiwan.
Thamotharan S; 2 Division of Neonatology and Developmental Biology, Department of Pediatrics, Neonatal Research Center of the UCLA Children's Discovery and Innovation Institute, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Ganguly A; 2 Division of Neonatology and Developmental Biology, Department of Pediatrics, Neonatal Research Center of the UCLA Children's Discovery and Innovation Institute, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Lam L; 3 Department of Molecular, Cell, and Developmental Biology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Montoya D; 3 Department of Molecular, Cell, and Developmental Biology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Pellegrini M; 3 Department of Molecular, Cell, and Developmental Biology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Devaskar SU; 2 Division of Neonatology and Developmental Biology, Department of Pediatrics, Neonatal Research Center of the UCLA Children's Discovery and Innovation Institute, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

Reprod Sci ; 25(4): 523-539, 2018 04.

Article en En | MEDLINE | ID: mdl-28693373

Asunto(s)

Peso al Nacer/genética; Metilación de ADN; Desarrollo Fetal/genética; Placenta/metabolismo; Epigénesis Genética; Femenino; Retardo del Crecimiento Fetal/genética; Retardo del Crecimiento Fetal/metabolismo; Expresión Génica; Regulación de la Expresión Génica; Humanos; Recién Nacido; Embarazo

Palabras clave

DNA methylation; developmental programming of cardiometabolic disease; intrauterine growth restriction (IUGR); large for gestational age (LGA); placenta

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Placenta / Peso al Nacer / Metilación de ADN / Desarrollo Fetal Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Newborn / Pregnancy Idioma: En Revista: Reprod Sci Asunto de la revista: MEDICINA REPRODUTIVA Año: 2018 Tipo del documento: Article País de afiliación: Taiwán

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