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Chronic Cigarette Smoke-Induced Epigenomic Changes Precede Sensitization of Bronchial Epithelial Cells to Single-Step Transformation by KRAS Mutations.
Vaz, Michelle; Hwang, Stephen Y; Kagiampakis, Ioannis; Phallen, Jillian; Patil, Ashwini; O'Hagan, Heather M; Murphy, Lauren; Zahnow, Cynthia A; Gabrielson, Edward; Velculescu, Victor E; Easwaran, Hariharan P; Baylin, Stephen B.
Afiliación
  • Vaz M; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Hwang SY; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Kagiampakis I; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Phallen J; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Patil A; Krieger School of Arts and Sciences, Baltimore, MD 21218, USA.
  • O'Hagan HM; Medical Sciences, Indiana University School of Medicine, Bloomington, IN 47405, USA; Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, IN 46202, USA.
  • Murphy L; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Zahnow CA; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Gabrielson E; Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Velculescu VE; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Easwaran HP; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Electronic address: heaswar2@jhmi.edu.
  • Baylin SB; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Electronic address: sbaylin@jhmi.edu.
Cancer Cell ; 32(3): 360-376.e6, 2017 09 11.
Article en En | MEDLINE | ID: mdl-28898697
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Bronquios / Fumar / Transformación Celular Neoplásica / Proteínas Proto-Oncogénicas p21(ras) / Células Epiteliales / Epigenómica / Mutación Límite: Animals / Humans / Male Idioma: En Revista: Cancer Cell Asunto de la revista: NEOPLASIAS Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Bronquios / Fumar / Transformación Celular Neoplásica / Proteínas Proto-Oncogénicas p21(ras) / Células Epiteliales / Epigenómica / Mutación Límite: Animals / Humans / Male Idioma: En Revista: Cancer Cell Asunto de la revista: NEOPLASIAS Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos