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Fumarate Hydratase Deletion in Pancreatic ß Cells Leads to Progressive Diabetes.
Adam, Julie; Ramracheya, Reshma; Chibalina, Margarita V; Ternette, Nicola; Hamilton, Alexander; Tarasov, Andrei I; Zhang, Quan; Rebelato, Eduardo; Rorsman, Nils J G; Martín-Del-Río, Rafael; Lewis, Amy; Özkan, Gizem; Do, Hyun Woong; Spégel, Peter; Saitoh, Kaori; Kato, Keiko; Igarashi, Kaori; Kessler, Benedikt M; Pugh, Christopher W; Tamarit-Rodriguez, Jorge; Mulder, Hindrik; Clark, Anne; Frizzell, Norma; Soga, Tomoyoshi; Ashcroft, Frances M; Silver, Andrew; Pollard, Patrick J; Rorsman, Patrik.
Afiliación
  • Adam J; Radcliffe Department of Medicine, OCDEM, Churchill Hospital, University of Oxford, Oxford OX3 7LE, UK; Nuffield Department of Medicine, Henry Wellcome Building for Molecular Physiology, University of Oxford, Oxford OX3 7BN, UK; Nuffield Department of Medicine, NDMRB, University of Oxford, Oxford OX3
  • Ramracheya R; Radcliffe Department of Medicine, OCDEM, Churchill Hospital, University of Oxford, Oxford OX3 7LE, UK.
  • Chibalina MV; Radcliffe Department of Medicine, OCDEM, Churchill Hospital, University of Oxford, Oxford OX3 7LE, UK.
  • Ternette N; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, UK.
  • Hamilton A; Radcliffe Department of Medicine, OCDEM, Churchill Hospital, University of Oxford, Oxford OX3 7LE, UK.
  • Tarasov AI; Radcliffe Department of Medicine, OCDEM, Churchill Hospital, University of Oxford, Oxford OX3 7LE, UK.
  • Zhang Q; Radcliffe Department of Medicine, OCDEM, Churchill Hospital, University of Oxford, Oxford OX3 7LE, UK.
  • Rebelato E; Radcliffe Department of Medicine, OCDEM, Churchill Hospital, University of Oxford, Oxford OX3 7LE, UK; Department of Biophysics, Federal University of Sao Paulo, Sao Paulo 04023-062, Brazil.
  • Rorsman NJG; Radcliffe Department of Medicine, OCDEM, Churchill Hospital, University of Oxford, Oxford OX3 7LE, UK.
  • Martín-Del-Río R; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Ramón y Cajal Hospital, Madrid, Spain.
  • Lewis A; Centre for Genomics and Child Health, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, UK.
  • Özkan G; Nuffield Department of Medicine, Henry Wellcome Building for Molecular Physiology, University of Oxford, Oxford OX3 7BN, UK.
  • Do HW; Radcliffe Department of Medicine, OCDEM, Churchill Hospital, University of Oxford, Oxford OX3 7LE, UK.
  • Spégel P; Centre for Analysis and Synthesis, Department of Chemistry, Lund University, Box 124, 221 00 Lund, Sweden.
  • Saitoh K; Institute for Advanced Biosciences, Keio University, 246-2 Mizukami, Tsuruoka, Yamagata 997-0052, Japan.
  • Kato K; Institute for Advanced Biosciences, Keio University, 246-2 Mizukami, Tsuruoka, Yamagata 997-0052, Japan.
  • Igarashi K; Institute for Advanced Biosciences, Keio University, 246-2 Mizukami, Tsuruoka, Yamagata 997-0052, Japan.
  • Kessler BM; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, UK.
  • Pugh CW; Nuffield Department of Medicine, Henry Wellcome Building for Molecular Physiology, University of Oxford, Oxford OX3 7BN, UK; Nuffield Department of Medicine, NDMRB, University of Oxford, Oxford OX3 7FZ, UK.
  • Tamarit-Rodriguez J; Biochemistry Department, School of Medicine, Complutense University of Madrid, 28040 Madrid, Spain.
  • Mulder H; Lund University Diabetes Centre, Unit of Molecular Metabolism, Clinical Research Centre, Malmo University Hospital, 20502 Malmo, Sweden.
  • Clark A; Radcliffe Department of Medicine, OCDEM, Churchill Hospital, University of Oxford, Oxford OX3 7LE, UK.
  • Frizzell N; Department of Pharmacology, Physiology & Neuroscience, School of Medicine, University of South Carolina, Columbia, SC 29208, USA.
  • Soga T; Institute for Advanced Biosciences, Keio University, 246-2 Mizukami, Tsuruoka, Yamagata 997-0052, Japan.
  • Ashcroft FM; Department of Physiology, Anatomy and Genetics, University of Oxford, Parks Road, Oxford OX1 3PT, UK.
  • Silver A; Centre for Genomics and Child Health, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, UK.
  • Pollard PJ; Nuffield Department of Medicine, Henry Wellcome Building for Molecular Physiology, University of Oxford, Oxford OX3 7BN, UK; Department of Physiology, Institute of Neuroscience and Physiology, University of Göteborg, 405 30 Göteborg, Sweden.
  • Rorsman P; Radcliffe Department of Medicine, OCDEM, Churchill Hospital, University of Oxford, Oxford OX3 7LE, UK; Department of Physiology, Institute of Neuroscience and Physiology, University of Göteborg, 405 30 Göteborg, Sweden. Electronic address: patrik.rorsman@hmc.ox.ac.uk.
Cell Rep ; 20(13): 3135-3148, 2017 Sep 26.
Article en En | MEDLINE | ID: mdl-28954230

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Islotes Pancreáticos / Diabetes Mellitus Tipo 2 / Células Secretoras de Insulina / Fumarato Hidratasa Límite: Animals / Humans Idioma: En Revista: Cell Rep Año: 2017 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Islotes Pancreáticos / Diabetes Mellitus Tipo 2 / Células Secretoras de Insulina / Fumarato Hidratasa Límite: Animals / Humans Idioma: En Revista: Cell Rep Año: 2017 Tipo del documento: Article