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Hydroxyurea differentially modulates activator and repressors of γ-globin gene in erythroblasts of responsive and non-responsive patients with sickle cell disease in correlation with Index of Hydroxyurea Responsiveness.
Zhu, Xingguo; Hu, Tianxiang; Ho, Meng Hsuan; Wang, Yongchao; Yu, Miao; Patel, Niren; Pi, Wenhu; Choi, Jeong-Hyeon; Xu, Hongyan; Ganapathy, Vadivel; Kutlar, Ferdane; Kutlar, Abdullah; Tuan, Dorothy.
Afiliación
  • Zhu X; Department of Biochemistry and Molecular Biology, Augusta University, GA, USA.
  • Hu T; Department of Biochemistry and Molecular Biology, Augusta University, GA, USA.
  • Ho MH; Department of Biochemistry and Molecular Biology, Augusta University, GA, USA.
  • Wang Y; School of Dentistry, Meharry Medical College, Nashville, TN, USA.
  • Yu M; Department of Biochemistry and Molecular Biology, Augusta University, GA, USA.
  • Patel N; Department of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, KY, USA.
  • Pi W; Georgia Cancer Research Center, Augusta University, GA, USA.
  • Choi JH; Division of Hematology/Oncology, Augusta University, GA, USA.
  • Xu H; Department of Biochemistry and Molecular Biology, Augusta University, GA, USA.
  • Ganapathy V; Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Kutlar F; Georgia Cancer Research Center, Augusta University, GA, USA.
  • Kutlar A; Department of Biostatistics, Augusta University, GA, USA.
  • Tuan D; Department of Biostatistics, Augusta University, GA, USA.
Haematologica ; 102(12): 1995-2004, 2017 12.
Article en En | MEDLINE | ID: mdl-28971909
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Eritroblastos / Regulación de la Expresión Génica / Gamma-Globinas / Hidroxiurea / Anemia de Células Falciformes Límite: Humans Idioma: En Revista: Haematologica Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Eritroblastos / Regulación de la Expresión Génica / Gamma-Globinas / Hidroxiurea / Anemia de Células Falciformes Límite: Humans Idioma: En Revista: Haematologica Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos