Clonal chromosomal aberrations in Philadelphia negative cells such as monosomy 7 and trisomy 8 may persist for years with no impact on the long term outcome in patients with chronic myeloid leukemia.

Wasilewska, Ewa M; Panasiuk, Barbara; Gniot, Michal; Sawicka, Anna; Kozlowska, Katarzyna; Lewandowski, Krzysztof; Kloczko, Janusz; Midro, Alina T

Wasilewska, Ewa M; Panasiuk, Barbara; Gniot, Michal; Sawicka, Anna; Kozlowska, Katarzyna; Lewandowski, Krzysztof; Kloczko, Janusz; Midro, Alina T.

Afiliación

Wasilewska EM; Department of Hematology, Medical University of Bialystok, 24A Sklodowskiej-Curie Street, 15-276 Bialystok, Poland. Electronic address: emewa79@gmail.com.
Panasiuk B; Department of Clinical Genetics, Medical University of Bialystok, 13 Waszyngtona Street, 15-089 Bialystok, Poland.
Gniot M; Department of Hematology and Bone Marrow Transplantation, University of Medical Sciences, 84 Szamarzewskiego Street, Poznan, Poland.
Sawicka A; Department of Clinical Genetics, Medical University of Bialystok, 13 Waszyngtona Street, 15-089 Bialystok, Poland.
Kozlowska K; Department of Hematology, Medical University of Bialystok, 24A Sklodowskiej-Curie Street, 15-276 Bialystok, Poland.
Lewandowski K; Department of Hematology and Bone Marrow Transplantation, University of Medical Sciences, 84 Szamarzewskiego Street, Poznan, Poland.
Kloczko J; Department of Hematology, Medical University of Bialystok, 24A Sklodowskiej-Curie Street, 15-276 Bialystok, Poland.
Midro AT; Department of Clinical Genetics, Medical University of Bialystok, 13 Waszyngtona Street, 15-089 Bialystok, Poland.

Cancer Genet ; 216-217: 1-9, 2017 Oct.

Article en En | MEDLINE | ID: mdl-29025581

Asunto(s)

Leucemia Mielógena Crónica BCR-ABL Positiva/genética; Leucemia Mielógena Crónica BCR-ABL Positiva/patología; Cromosoma Filadelfia; Trisomía/genética; Anciano; Deleción Cromosómica; Cromosomas Humanos Par 7/genética; Cromosomas Humanos Par 8/genética; Células Clonales; Análisis Citogenético; Femenino; Humanos; Masculino; Persona de Mediana Edad; Resultado del Tratamiento

Palabras clave

Chronic myeloid leukemia (CML); TKI treatment; chromosomal abnormalities in Philadelphia negative cells; monosomy 7; trisomy 8

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trisomía / Cromosoma Filadelfia / Leucemia Mielógena Crónica BCR-ABL Positiva Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Cancer Genet Año: 2017 Tipo del documento: Article

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