Site-directed RNA repair of endogenous Mecp2 RNA in neurons.

Sinnamon, John R; Kim, Susan Y; Corson, Glen M; Song, Zhen; Nakai, Hiroyuki; Adelman, John P; Mandel, Gail

Sinnamon, John R; Kim, Susan Y; Corson, Glen M; Song, Zhen; Nakai, Hiroyuki; Adelman, John P; Mandel, Gail.

Afiliación

Sinnamon JR; Vollum Institute, Oregon Health and Science University, Portland, OR 97239.
Kim SY; Vollum Institute, Oregon Health and Science University, Portland, OR 97239.
Corson GM; Vollum Institute, Oregon Health and Science University, Portland, OR 97239.
Song Z; Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, OR 97239.
Nakai H; Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, OR 97239.
Adelman JP; Vollum Institute, Oregon Health and Science University, Portland, OR 97239.
Mandel G; Vollum Institute, Oregon Health and Science University, Portland, OR 97239; mandelg@ohsu.edu.

Proc Natl Acad Sci U S A ; 114(44): E9395-E9402, 2017 10 31.

Article en En | MEDLINE | ID: mdl-29078406

Asunto(s)

Proteína 2 de Unión a Metil-CpG/genética; Neuronas/fisiología; ARN/genética; Adenosina Desaminasa/genética; Animales; Células Cultivadas; Metilación de ADN/genética; Modelos Animales de Enfermedad; Humanos; Ratones; Mutación/genética; ARN Mensajero/genética; Proteínas de Unión al ARN/genética; Síndrome de Rett/genética

Palabras clave

ADAR2; MeCP2; RNA editing; Rett syndrome

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: ARN / Proteína 2 de Unión a Metil-CpG / Neuronas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2017 Tipo del documento: Article

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