Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase.

Dulic, Morana; Cvetesic, Nevena; Zivkovic, Igor; Palencia, Andrés; Cusack, Stephen; Bertosa, Branimir; Gruic-Sovulj, Ita

Dulic, Morana; Cvetesic, Nevena; Zivkovic, Igor; Palencia, Andrés; Cusack, Stephen; Bertosa, Branimir; Gruic-Sovulj, Ita.

Afiliación

Dulic M; Department of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, 10000 Zagreb, Croatia.
Cvetesic N; Department of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, 10000 Zagreb, Croatia.
Zivkovic I; Department of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, 10000 Zagreb, Croatia.
Palencia A; European Molecular Biology Laboratory, Grenoble Outstation and Unit of Virus Host-Cell Interactions, University of Grenoble Alpes-EMBL-CNRS, UMI 3265, Grenoble Cedex 9, France.
Cusack S; European Molecular Biology Laboratory, Grenoble Outstation and Unit of Virus Host-Cell Interactions, University of Grenoble Alpes-EMBL-CNRS, UMI 3265, Grenoble Cedex 9, France.
Bertosa B; Department of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, 10000 Zagreb, Croatia.
Gruic-Sovulj I; Department of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, 10000 Zagreb, Croatia. Electronic address: gruic@chem.pmf.hr.

J Mol Biol ; 430(1): 1-16, 2018 01 05.

Article en En | MEDLINE | ID: mdl-29111343

Asunto(s)

Aminoacil-ARNt Sintetasas/genética; Leucina-ARNt Ligasa/genética; Aminoacil-ARN de Transferencia/genética; Especificidad por Sustrato/genética; Acilación/genética; Aminoácidos/genética; Aminoacilación/genética; Sitios de Unión/genética; Escherichia coli/genética; Hidrólisis; Cinética

Palabras clave

aminoacyl-tRNA synthetases; catalytic RNA; norvaline; proofreading; substrate-assisted catalysis

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Especificidad por Sustrato / Aminoacil-ARN de Transferencia / Aminoacil-ARNt Sintetasas / Leucina-ARNt Ligasa Idioma: En Revista: J Mol Biol Año: 2018 Tipo del documento: Article País de afiliación: Croacia

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