Mechanisms of Sustained Neutrophilia in Patient WHIM-09, Cured of WHIM Syndrome by Chromothripsis.

Liu, Qian; Li, Zhanzhuo; Y Yang, Alexander; Gao, Ji-Liang; S Velez, Daniel; J Cho, Elena; McDermott, David H; Murphy, Philip M

Liu, Qian; Li, Zhanzhuo; Y Yang, Alexander; Gao, Ji-Liang; S Velez, Daniel; J Cho, Elena; McDermott, David H; Murphy, Philip M.

Afiliación

Liu Q; Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bldg 10, Room 11N113, NIH, Bethesda, MD, 20892, USA.
Li Z; Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bldg 10, Room 11N113, NIH, Bethesda, MD, 20892, USA.
Y Yang A; Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bldg 10, Room 11N113, NIH, Bethesda, MD, 20892, USA.
Gao JL; Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bldg 10, Room 11N113, NIH, Bethesda, MD, 20892, USA.
S Velez D; Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bldg 10, Room 11N113, NIH, Bethesda, MD, 20892, USA.
J Cho E; Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bldg 10, Room 11N113, NIH, Bethesda, MD, 20892, USA.
McDermott DH; Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bldg 10, Room 11N113, NIH, Bethesda, MD, 20892, USA.
Murphy PM; Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bldg 10, Room 11N113, NIH, Bethesda, MD, 20892, USA. pmm@nih.gov.

J Clin Immunol ; 38(1): 77-87, 2018 01.

Article en En | MEDLINE | ID: mdl-29177911

Asunto(s)

Cromotripsis; Células Madre Hematopoyéticas/fisiología; Síndromes de Inmunodeficiencia/diagnóstico; Mutación/genética; Neutrófilos/fisiología; Receptores CXCR4/genética; Verrugas/diagnóstico; Alelos; Animales; Diferenciación Celular/genética; Niño; Modelos Animales de Enfermedad; Femenino; Haploinsuficiencia; Humanos; Síndromes de Inmunodeficiencia/genética; Ratones; Ratones Endogámicos C57BL; Ratones Noqueados; Enfermedades de Inmunodeficiencia Primaria; Esplenectomía; Verrugas/genética

Palabras clave

CXCR4; HSC; Neutrophilia; WHIM syndrome; chromothripsis; mutation

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Madre Hematopoyéticas / Verrugas / Receptores CXCR4 / Cromotripsis / Síndromes de Inmunodeficiencia / Mutación / Neutrófilos Tipo de estudio: Prognostic_studies Límite: Animals / Child / Female / Humans Idioma: En Revista: J Clin Immunol Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos

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