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Overview of the improvement of the ring-stage survival assay-a novel phenotypic assay for the detection of artemisinin-resistant Plasmodium falciparum.
Zhang, Jie; Feng, Guo-Hua; Zou, Chun-Yan; Su, Pin-Can; Liu, Huai-E; Yang, Zhao-Qing.
Afiliación
  • Zhang J; Department of Pathogen Biology and Immunology, Kunming Medical University, Kunming Yunnan 650500, China.
  • Feng GH; Biomedical Engineering Research Center, Kunming Medical University, Kunming Yunnan 650500, China.
  • Zou CY; Guangxi Zhuang Autonomous Region People's Hospital, Nanning Guangxi 530021, China.
  • Su PC; Transfusion Medicine Research Department, Yunnan Kunming Blood Center, Kunming Yunnan 650500, China.
  • Liu HE; Department of Pathogen Biology and Immunology, Kunming Medical University, Kunming Yunnan 650500, China.
  • Yang ZQ; Department of Infectious Diseases, The First Affiliated Hospital, Kunming Medical University, Kunming Yunnan 650032, China.
Zool Res ; 38(6): 317-320, 2017 Nov 18.
Article en En | MEDLINE | ID: mdl-29280362
ABSTRACT
Artemisinin resistance in Plasmodium falciparum threatens the remarkable efficacy of artemisinin-based combination therapies worldwide. Thus, greater insight into the resistance mechanism using monitoring tools is essential. The ring-stage survival assay is used for phenotyping artemisinin-resistance or decreased artemisinin sensitivity. Here, we review the progress of this measurement assay and explore its limitations and potential applications.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Plasmodium falciparum / Resistencia a Medicamentos / Artemisininas / Antimaláricos Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Zool Res Año: 2017 Tipo del documento: Article País de afiliación: China

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Plasmodium falciparum / Resistencia a Medicamentos / Artemisininas / Antimaláricos Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Zool Res Año: 2017 Tipo del documento: Article País de afiliación: China