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Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis.
Ingold, Irina; Berndt, Carsten; Schmitt, Sabine; Doll, Sebastian; Poschmann, Gereon; Buday, Katalin; Roveri, Antonella; Peng, Xiaoxiao; Porto Freitas, Florencio; Seibt, Tobias; Mehr, Lisa; Aichler, Michaela; Walch, Axel; Lamp, Daniel; Jastroch, Martin; Miyamoto, Sayuri; Wurst, Wolfgang; Ursini, Fulvio; Arnér, Elias S J; Fradejas-Villar, Noelia; Schweizer, Ulrich; Zischka, Hans; Friedmann Angeli, José Pedro; Conrad, Marcus.
Afiliación
  • Ingold I; Helmholtz Zentrum München, Institute of Developmental Genetics, 85764 Neuherberg, Germany.
  • Berndt C; Heinrich-Heine University, Department of Neurology, Medical Faculty, 40255 Düsseldorf, Germany.
  • Schmitt S; Institute of Toxicology and Environmental Hygiene, Technical University of Munich, 80802 Munich, Germany.
  • Doll S; Helmholtz Zentrum München, Institute of Developmental Genetics, 85764 Neuherberg, Germany.
  • Poschmann G; Heinrich-Heine University, Molecular Proteomics Laboratory, Biomedical Research Center (BMFZ), 40225 Düsseldorf, Germany.
  • Buday K; Helmholtz Zentrum München, Institute of Developmental Genetics, 85764 Neuherberg, Germany.
  • Roveri A; Department of Molecular Medicine, University of Padova, Padova, Italy.
  • Peng X; CVMD Translational Medicine Unit, Early Clinical Development, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.
  • Porto Freitas F; Helmholtz Zentrum München, Institute of Developmental Genetics, 85764 Neuherberg, Germany.
  • Seibt T; Department of Nephrology, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, 80336 München, Germany.
  • Mehr L; Helmholtz Zentrum München, Institute of Developmental Genetics, 85764 Neuherberg, Germany.
  • Aichler M; Helmholtz Zentrum München, Research Unit of Analytical Pathology, 85764 Neuherberg, Germany.
  • Walch A; Helmholtz Zentrum München, Research Unit of Analytical Pathology, 85764 Neuherberg, Germany.
  • Lamp D; Helmholtz Zentrum München, Helmholtz Diabetes Center and German Diabetes Center (DZD), 85764 Neuherberg, Germany; Helmholtz Zentrum München, Institute for Diabetes and Obesity, 85748 Garching, Germany.
  • Jastroch M; Helmholtz Zentrum München, Helmholtz Diabetes Center and German Diabetes Center (DZD), 85764 Neuherberg, Germany; Helmholtz Zentrum München, Institute for Diabetes and Obesity, 85748 Garching, Germany.
  • Miyamoto S; Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil.
  • Wurst W; Helmholtz Zentrum München, Institute of Developmental Genetics, 85764 Neuherberg, Germany; German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany; Technische Universität München-Weihenstephan, Chair of Developmental Genetics, c/o Helmholtz Zentrum München, 85764 Neuherberg, Germa
  • Ursini F; Department of Molecular Medicine, University of Padova, Padova, Italy.
  • Arnér ESJ; Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77 Stockholm, Sweden.
  • Fradejas-Villar N; Rheinische Friedrich-Wilhelms-University Bonn, Institute for Biochemistry and Molecular Biology, 53115 Bonn, Germany.
  • Schweizer U; Rheinische Friedrich-Wilhelms-University Bonn, Institute for Biochemistry and Molecular Biology, 53115 Bonn, Germany.
  • Zischka H; Institute of Toxicology and Environmental Hygiene, Technical University of Munich, 80802 Munich, Germany; Helmholtz Zentrum München, Institute of Molecular Toxicology and Pharmacology, 85764 Neuherberg, Germany.
  • Friedmann Angeli JP; Helmholtz Zentrum München, Institute of Developmental Genetics, 85764 Neuherberg, Germany.
  • Conrad M; Helmholtz Zentrum München, Institute of Developmental Genetics, 85764 Neuherberg, Germany. Electronic address: marcus.conrad@helmholtz-muenchen.de.
Cell ; 172(3): 409-422.e21, 2018 01 25.
Article en En | MEDLINE | ID: mdl-29290465
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Convulsiones / Selenio / Apoptosis / Glutatión Peroxidasa Tipo de estudio: Etiology_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Cell Año: 2018 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Convulsiones / Selenio / Apoptosis / Glutatión Peroxidasa Tipo de estudio: Etiology_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Cell Año: 2018 Tipo del documento: Article País de afiliación: Alemania