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Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming.
Christ, Anette; Günther, Patrick; Lauterbach, Mario A R; Duewell, Peter; Biswas, Debjani; Pelka, Karin; Scholz, Claus J; Oosting, Marije; Haendler, Kristian; Baßler, Kevin; Klee, Kathrin; Schulte-Schrepping, Jonas; Ulas, Thomas; Moorlag, Simone J C F M; Kumar, Vinod; Park, Min Hi; Joosten, Leo A B; Groh, Laszlo A; Riksen, Niels P; Espevik, Terje; Schlitzer, Andreas; Li, Yang; Fitzgerald, Michael L; Netea, Mihai G; Schultze, Joachim L; Latz, Eicke.
Afiliación
  • Christ A; Institute of Innate Immunity, University Hospital Bonn, University of Bonn, 53127 Bonn, Germany; Department of Infectious Diseases & Immunology, UMass Medical School, Worcester, MA 01605, USA.
  • Günther P; Department for Genomics & Immunoregulation, and Myeloid Cell Biology, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany.
  • Lauterbach MAR; Institute of Innate Immunity, University Hospital Bonn, University of Bonn, 53127 Bonn, Germany.
  • Duewell P; Center of Integrated Protein Science Munich (CIPSM) and Division of Clinical Pharmacology, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, 80337 Munich, Germany.
  • Biswas D; Department of Infectious Diseases & Immunology, UMass Medical School, Worcester, MA 01605, USA.
  • Pelka K; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Scholz CJ; Department for Genomics & Immunoregulation, and Myeloid Cell Biology, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany.
  • Oosting M; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
  • Haendler K; Department for Genomics & Immunoregulation, and Myeloid Cell Biology, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany.
  • Baßler K; Department for Genomics & Immunoregulation, and Myeloid Cell Biology, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany.
  • Klee K; Department for Genomics & Immunoregulation, and Myeloid Cell Biology, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany.
  • Schulte-Schrepping J; Department for Genomics & Immunoregulation, and Myeloid Cell Biology, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany.
  • Ulas T; Department for Genomics & Immunoregulation, and Myeloid Cell Biology, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany.
  • Moorlag SJCFM; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
  • Kumar V; Department of Genetics, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, the Netherlands.
  • Park MH; Lipid Metabolism Unit, Center for Computational and Integrative Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A&M University, 77845 College Station, TX, USA.
  • Joosten LAB; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
  • Groh LA; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
  • Riksen NP; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.
  • Espevik T; Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, 7491 Trondheim, Norway.
  • Schlitzer A; Department for Genomics & Immunoregulation, and Myeloid Cell Biology, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany.
  • Li Y; Department of Genetics, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, the Netherlands.
  • Fitzgerald ML; Lipid Metabolism Unit, Center for Computational and Integrative Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
  • Netea MG; Department for Genomics & Immunoregulation, and Myeloid Cell Biology, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA Nijmegen, the Netherl
  • Schultze JL; Department for Genomics & Immunoregulation, and Myeloid Cell Biology, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.
  • Latz E; Institute of Innate Immunity, University Hospital Bonn, University of Bonn, 53127 Bonn, Germany; Department of Infectious Diseases & Immunology, UMass Medical School, Worcester, MA 01605, USA; Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, 7491 Trondhe
Cell ; 172(1-2): 162-175.e14, 2018 01 11.
Article en En | MEDLINE | ID: mdl-29328911
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Epigénesis Genética / Reprogramación Celular / Dieta Occidental / Proteína con Dominio Pirina 3 de la Familia NLR / Inmunidad Innata / Memoria Inmunológica Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Cell Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Epigénesis Genética / Reprogramación Celular / Dieta Occidental / Proteína con Dominio Pirina 3 de la Familia NLR / Inmunidad Innata / Memoria Inmunológica Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Cell Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos