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The proteoglycan biglycan mediates inflammatory response by activating TLR-4 in human chondrocytes: Inhibition by specific siRNA and high polymerized Hyaluronan.
Avenoso, Angela; D'Ascola, Angela; Scuruchi, Michele; Mandraffino, Giuseppe; Calatroni, Alberto; Saitta, Antonino; Campo, Salvatore; Campo, Giuseppe M.
Afiliación
  • Avenoso A; Department of Biomedical and Dental Sciences and Morphofunctional Images, Policlinico Universitario, University of Messina, 98125 Messina, Italy.
  • D'Ascola A; Department of Clinical and Experimental Medicine, University of Messina, Policlinico Universitario, 98125 Messina, Italy.
  • Scuruchi M; Department of Clinical and Experimental Medicine, University of Messina, Policlinico Universitario, 98125 Messina, Italy.
  • Mandraffino G; Department of Clinical and Experimental Medicine, University of Messina, Policlinico Universitario, 98125 Messina, Italy.
  • Calatroni A; Department of Clinical and Experimental Medicine, University of Messina, Policlinico Universitario, 98125 Messina, Italy.
  • Saitta A; Department of Clinical and Experimental Medicine, University of Messina, Policlinico Universitario, 98125 Messina, Italy.
  • Campo S; Department of Biomedical and Dental Sciences and Morphofunctional Images, Policlinico Universitario, University of Messina, 98125 Messina, Italy.
  • Campo GM; Department of Clinical and Experimental Medicine, University of Messina, Policlinico Universitario, 98125 Messina, Italy. Electronic address: gcampo@unime.it.
Arch Biochem Biophys ; 640: 75-82, 2018 02 15.
Article en En | MEDLINE | ID: mdl-29339093
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Polímeros / Mediadores de Inflamación / Condrocitos / ARN Interferente Pequeño / Receptor Toll-Like 4 / Biglicano / Ácido Hialurónico / Inflamación Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Arch Biochem Biophys Año: 2018 Tipo del documento: Article País de afiliación: Italia
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Polímeros / Mediadores de Inflamación / Condrocitos / ARN Interferente Pequeño / Receptor Toll-Like 4 / Biglicano / Ácido Hialurónico / Inflamación Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Arch Biochem Biophys Año: 2018 Tipo del documento: Article País de afiliación: Italia