Beta carotene-loaded zein nanoparticles to improve the biopharmaceutical attributes and to abolish the toxicity of methotrexate: a preclinical study for breast cancer.

Jain, Ashay; Sharma, Gajanand; Kushwah, Varun; Ghoshal, Gargi; Jain, Atul; Singh, Bhupinder; Shivhare, U S; Jain, Sanyog; Katare, O P

Jain, Ashay; Sharma, Gajanand; Kushwah, Varun; Ghoshal, Gargi; Jain, Atul; Singh, Bhupinder; Shivhare, U S; Jain, Sanyog; Katare, O P.

Afiliación

Jain A; a University Institute of Pharmaceutical Sciences, Panjab University , Chandigarh , India.
Sharma G; b UGC-Centre of Excellence in Applications of Nanomaterials, Nanoparticles and Nanocomposites, Panjab University , Chandigarh , India.
Kushwah V; c Dr. S. S. Bhatnagar University Institute of Chemical Engineering & Technology, Panjab University , Chandigarh , India.
Ghoshal G; a University Institute of Pharmaceutical Sciences, Panjab University , Chandigarh , India.
Jain A; d Department of Pharmaceutics , National Institute of Pharmaceutical Education and Research , SAS Nagar , India.
Singh B; c Dr. S. S. Bhatnagar University Institute of Chemical Engineering & Technology, Panjab University , Chandigarh , India.
Shivhare US; b UGC-Centre of Excellence in Applications of Nanomaterials, Nanoparticles and Nanocomposites, Panjab University , Chandigarh , India.
Jain S; c Dr. S. S. Bhatnagar University Institute of Chemical Engineering & Technology, Panjab University , Chandigarh , India.
Katare OP; c Dr. S. S. Bhatnagar University Institute of Chemical Engineering & Technology, Panjab University , Chandigarh , India.

Artif Cells Nanomed Biotechnol ; 46(sup1): 402-412, 2018.

Article en En | MEDLINE | ID: mdl-29361842

Asunto(s)

Neoplasias de la Mama/patología; Portadores de Fármacos/química; Metotrexato/química; Metotrexato/farmacología; Zeína/química; beta Caroteno/química; Animales; Apoptosis/efectos de los fármacos; Disponibilidad Biológica; Transporte Biológico; Supervivencia Celular/efectos de los fármacos; Liberación de Fármacos; Femenino; Humanos; Células MCF-7; Metotrexato/farmacocinética; Metotrexato/toxicidad; Ratas; Ratas Wistar

Palabras clave

Beta carotene; bioavailability; cancer; methotrexate; nanoparticles; zein

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Zeína / Neoplasias de la Mama / Portadores de Fármacos / Metotrexato / Beta Caroteno Límite: Animals / Female / Humans Idioma: En Revista: Artif Cells Nanomed Biotechnol Año: 2018 Tipo del documento: Article País de afiliación: India

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