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Discovery of GDC-0853: A Potent, Selective, and Noncovalent Bruton's Tyrosine Kinase Inhibitor in Early Clinical Development.
Crawford, James J; Johnson, Adam R; Misner, Dinah L; Belmont, Lisa D; Castanedo, Georgette; Choy, Regina; Coraggio, Melis; Dong, Liming; Eigenbrot, Charles; Erickson, Rebecca; Ghilardi, Nico; Hau, Jonathan; Katewa, Arna; Kohli, Pawan Bir; Lee, Wendy; Lubach, Joseph W; McKenzie, Brent S; Ortwine, Daniel F; Schutt, Leah; Tay, Suzanne; Wei, BinQing; Reif, Karin; Liu, Lichuan; Wong, Harvey; Young, Wendy B.
Afiliación
  • Crawford JJ; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Johnson AR; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Misner DL; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Belmont LD; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Castanedo G; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Choy R; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Coraggio M; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Dong L; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Eigenbrot C; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Erickson R; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Ghilardi N; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Hau J; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Katewa A; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Kohli PB; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Lee W; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Lubach JW; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • McKenzie BS; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Ortwine DF; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Schutt L; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Tay S; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Wei B; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Reif K; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Liu L; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Wong H; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
  • Young WB; Genentech, Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
J Med Chem ; 61(6): 2227-2245, 2018 03 22.
Article en En | MEDLINE | ID: mdl-29457982
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piperazinas / Piridonas / Inhibidores de Proteínas Quinasas / Agammaglobulinemia Tirosina Quinasa / Antiinflamatorios Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piperazinas / Piridonas / Inhibidores de Proteínas Quinasas / Agammaglobulinemia Tirosina Quinasa / Antiinflamatorios Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos