Impact of the third generation cryoballoon on atrial fibrillation ablation: An useful tool?
Indian Pacing Electrophysiol J
; 18(4): 127-132, 2018.
Article
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| MEDLINE
| ID: mdl-29476904
ABSTRACT
BACKGROUND:
Third-generation cryoballoon (CB3) is characterized by a 40% shorter distal tip designed to increase the rate of pulmonary veins real-time signal recording in order to measure time necessary to isolate veins, the "Time to effect" (TTE). Few data are currently available on clinical follow up of CB3 treated patients.METHODS:
Sixtyeight consecutive patients (mean age 57.8⯱â¯9.6 years, 48 male) with paroxysmal or persistent atrial fibrillation (AF) were enrolled. Thirthyfour (25 paroxysmal AF) underwent to a 28 mmCB3 pulmonary veins isolation and were compared to 34 treated (21 paroxysmal AF) with 28 mmCB2.RESULTS:
CB3 use was correlated to significant increase of the possibility to measure TTE in every treated veins (left superior 82,35% vs 23,53%, left inferior 70,59% vs 38,24%, right superior 58,82% vs 14,71%, right inferior 52,94% vs 17,65%). When it is measured, TTE wasn't different between two groups. Higher nadir temperature was observed in CB3 patients (-39.4⯱â¯5.2⯰C vs -43.0⯱â¯7.2⯰C, pâ¯=â¯0.03). CB3 procedures were shorter (91.4⯱â¯21.7 vs 110.9⯱â¯31.8â¯min, pâ¯=â¯0.018), with a significant reduction in cryoenergy delivery time (24.2⯱â¯8.5 vs 20.3⯱â¯6.7â¯min, pâ¯<â¯0.05), and a significant reduction in left atrium dwell time (59.3⯱â¯9.8 vs 69.3⯱â¯10.8â¯min, pâ¯=â¯0.02, pâ¯<â¯0.05). At one year follow up period the Kaplan-Meier curve didn't show any significant difference in AF-free survival (Log pâ¯=â¯0,49).CONCLUSIONS:
Novel CB3 is a useful tool in order to simplify AF cryoballoon ablation when compared to second generation cryoballoon, as observed in our experience. Follow up data seem confirm a clinical CB3 efficacy at least comparable CB2.
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1
Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Indian Pacing Electrophysiol J
Año:
2018
Tipo del documento:
Article
País de afiliación:
Italia