Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation.

Mohandas, Namitha; Bass-Stringer, Sebastian; Maksimovic, Jovana; Crompton, Kylie; Loke, Yuk J; Walstab, Janet; Reid, Susan M; Amor, David J; Reddihough, Dinah; Craig, Jeffrey M

Mohandas, Namitha; Bass-Stringer, Sebastian; Maksimovic, Jovana; Crompton, Kylie; Loke, Yuk J; Walstab, Janet; Reid, Susan M; Amor, David J; Reddihough, Dinah; Craig, Jeffrey M.

Afiliación

Mohandas N; Environmental and Genetic Epidemiology Research, Murdoch Children's Research Institute, Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052 Australia.
Bass-Stringer S; 2Department of Paediatrics, The University of Melbourne, Flemington Road, Parkville, Victoria 3052 Australia.
Maksimovic J; Environmental and Genetic Epidemiology Research, Murdoch Children's Research Institute, Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052 Australia.
Crompton K; 2Department of Paediatrics, The University of Melbourne, Flemington Road, Parkville, Victoria 3052 Australia.
Loke YJ; Bioinformatics Group, Murdoch Children's Research Institute, Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052 Australia.
Walstab J; 2Department of Paediatrics, The University of Melbourne, Flemington Road, Parkville, Victoria 3052 Australia.
Reid SM; 4Developmental Disability and Rehabilitation Research, Murdoch Children's Research Institute, Flemington Road, Parkville, Victoria 3052 Australia.
Amor DJ; 5Neurodevelopment and Disability, The Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052 Australia.
Reddihough D; Environmental and Genetic Epidemiology Research, Murdoch Children's Research Institute, Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052 Australia.
Craig JM; 2Department of Paediatrics, The University of Melbourne, Flemington Road, Parkville, Victoria 3052 Australia.

Clin Epigenetics ; 10: 25, 2018.

Article en En | MEDLINE | ID: mdl-29484035

Asunto(s)

Proteínas Adaptadoras del Transporte Vesicular/genética; Parálisis Cerebral/genética; Metilación de ADN; Enfermedades en Gemelos/genética; Epigenómica/métodos; Linfotoxina-alfa/genética; Gemelos Monocigóticos/genética; Islas de CpG; Epigénesis Genética; Femenino; Humanos; Recién Nacido; Masculino; Análisis de Secuencia por Matrices de Oligonucleótidos/métodos; Regiones Promotoras Genéticas; Programas Informáticos; Sitio de Iniciación de la Transcripción; Secuenciación Completa del Genoma/métodos

Palabras clave

Cerebral palsy; DNA methylation; Discordant twins; Epigenetics; Inflammation

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Gemelos Monocigóticos / Parálisis Cerebral / Linfotoxina-alfa / Metilación de ADN / Proteínas Adaptadoras del Transporte Vesicular / Enfermedades en Gemelos / Epigenómica Tipo de estudio: Prognostic_studies Límite: Female / Humans / Male / Newborn Idioma: En Revista: Clin Epigenetics Año: 2018 Tipo del documento: Article

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