Posaconazole-Induced Pseudohyperaldosteronism.
Antimicrob Agents Chemother
; 62(5)2018 05.
Article
en En
| MEDLINE
| ID: mdl-29530850
ABSTRACT
A woman in her late 60s with disseminated histoplasmosis was treated with posaconazole because first-line therapies were not tolerated. She subsequently presented with decompensated heart failure, hypertension, and hypokalemia. Laboratory tests revealed low renin and aldosterone levels. A potential mechanism is inhibition of the enzyme 11ß-hydroxysteroid dehydrogenase 2, with resultant apparent mineralocorticoid excess.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Triazoles
/
Síndrome de Exceso Aparente de Mineralocorticoides
/
Insuficiencia Cardíaca
/
Hidroxiesteroide Deshidrogenasas
/
Hiperaldosteronismo
/
Hipertensión
/
Hipopotasemia
/
Antifúngicos
Tipo de estudio:
Diagnostic_studies
Límite:
Aged
/
Humans
Idioma:
En
Revista:
Antimicrob Agents Chemother
Año:
2018
Tipo del documento:
Article
País de afiliación:
Estados Unidos