Your browser doesn't support javascript.
loading
Secondary metabolites from Antarctic marine-derived fungus Penicillium crustosum HDN153086.
Liu, Cong-Cong; Zhang, Zhen-Zhen; Feng, Yan-Yan; Gu, Qian-Qun; Li, De-Hai; Zhu, Tian-Jiao.
Afiliación
  • Liu CC; a Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China , Qingdao , P. R. China.
  • Zhang ZZ; a Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China , Qingdao , P. R. China.
  • Feng YY; a Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China , Qingdao , P. R. China.
  • Gu QQ; a Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China , Qingdao , P. R. China.
  • Li DH; a Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China , Qingdao , P. R. China.
  • Zhu TJ; b Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology , Qingdao , P. R. China.
Nat Prod Res ; 33(3): 414-419, 2019 Feb.
Article en En | MEDLINE | ID: mdl-29600717
ABSTRACT
A new polyene compound (1) and a new diketopiperazine (2), as well as three known compounds (3-5), were isolated from the Antarctic marine-derived fungus Penicillium crustosum HDN153086. The structures of 1-5 were deduced based on MS, NMR and TD-DFT calculations of specific ECD spectra. These compounds were evaluated for their cytotoxic activities against K562 cell line and only compound 2 exhibited cytotoxicity against K562 cell, with IC50 value of 12.7 µM.
Asunto(s)
Palabras clave
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Penicillium / Polienos / Dicetopiperazinas Límite: Humans Idioma: En Revista: Nat Prod Res Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Penicillium / Polienos / Dicetopiperazinas Límite: Humans Idioma: En Revista: Nat Prod Res Año: 2019 Tipo del documento: Article