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A novel three-dimensional high-throughput screening approach identifies inducers of a mutant KRAS selective lethal phenotype.
Kota, Smitha; Hou, Shurong; Guerrant, William; Madoux, Franck; Troutman, Scott; Fernandez-Vega, Virneliz; Alekseeva, Nina; Madala, Neeharika; Scampavia, Louis; Kissil, Joseph; Spicer, Timothy P.
Afiliación
  • Kota S; Department of Molecular Medicine, The Scripps Research Institute, Florida, USA.
  • Hou S; Department of Molecular Medicine, The Scripps Research Institute, Florida, USA.
  • Guerrant W; Department of Molecular Medicine, The Scripps Research Institute, Florida, USA.
  • Madoux F; Department of Molecular Medicine, The Scripps Research Institute, Florida, USA.
  • Troutman S; Amgen Inc., Thousand Oaks, CA, USA.
  • Fernandez-Vega V; Department of Molecular Medicine, The Scripps Research Institute, Florida, USA.
  • Alekseeva N; Department of Molecular Medicine, The Scripps Research Institute, Florida, USA.
  • Madala N; Department of Molecular Medicine, The Scripps Research Institute, Florida, USA.
  • Scampavia L; Department of Molecular Medicine, The Scripps Research Institute, Florida, USA.
  • Kissil J; Department of Molecular Medicine, The Scripps Research Institute, Florida, USA.
  • Spicer TP; Department of Molecular Medicine, The Scripps Research Institute, Florida, USA. jkissil@scripps.edu.
Oncogene ; 37(32): 4372-4384, 2018 08.
Article en En | MEDLINE | ID: mdl-29743592

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas p21(ras) / Mutación Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas p21(ras) / Mutación Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos