The disorderly conduct of Hsc70 and its interaction with the Alzheimer's-related Tau protein.

Taylor, Isabelle R; Ahmad, Atta; Wu, Taia; Nordhues, Bryce A; Bhullar, Anup; Gestwicki, Jason E; Zuiderweg, Erik R P

Taylor, Isabelle R; Ahmad, Atta; Wu, Taia; Nordhues, Bryce A; Bhullar, Anup; Gestwicki, Jason E; Zuiderweg, Erik R P.

Afiliación

Taylor IR; the Institute for Neurodegenerative Disease, University of California at San Francisco, San Francisco, California 94158, and.
Ahmad A; From the Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109.
Wu T; the Institute for Neurodegenerative Disease, University of California at San Francisco, San Francisco, California 94158, and.
Nordhues BA; the Department of Molecular Medicine and Byrd Alzheimer's Institute, University of South Florida, Tampa, Florida 33613.
Bhullar A; From the Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109.
Gestwicki JE; the Institute for Neurodegenerative Disease, University of California at San Francisco, San Francisco, California 94158, and Jason.Gestwicki@ucsf.edu.
Zuiderweg ERP; From the Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109, zuiderwe@umich.edu.

J Biol Chem ; 293(27): 10796-10809, 2018 07 06.

Article en En | MEDLINE | ID: mdl-29764935

Asunto(s)

Proteínas del Choque Térmico HSC70/metabolismo; Pliegue de Proteína; Dominios y Motivos de Interacción de Proteínas; Proteínas tau/metabolismo; Adenosina Trifosfato/metabolismo; Enfermedad de Alzheimer/metabolismo; Enfermedad de Alzheimer/patología; Sitios de Unión; Cristalografía por Rayos X; Proteínas del Choque Térmico HSC70/química; Proteínas del Choque Térmico HSC70/genética; Humanos; Unión Proteica; Conformación Proteica; Proteínas tau/química; Proteínas tau/genética

Palabras clave

chaperone; microtubule-associated protein (MAP); nuclear magnetic resonance (NMR); protein complex; protein conformation

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas tau / Pliegue de Proteína / Proteínas del Choque Térmico HSC70 / Dominios y Motivos de Interacción de Proteínas Límite: Humans Idioma: En Revista: J Biol Chem Año: 2018 Tipo del documento: Article

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