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SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins.
Yan, Su; Elmes, Matthew W; Tong, Simon; Hu, Kongzhen; Awwa, Monaf; Teng, Gary Y H; Jing, Yunrong; Freitag, Matthew; Gan, Qianwen; Clement, Timothy; Wei, Longfei; Sweeney, Joseph M; Joseph, Olivia M; Che, Joyce; Carbonetti, Gregory S; Wang, Liqun; Bogdan, Diane M; Falcone, Jerome; Smietalo, Norbert; Zhou, Yuchen; Ralph, Brian; Hsu, Hao-Chi; Li, Huilin; Rizzo, Robert C; Deutsch, Dale G; Kaczocha, Martin; Ojima, Iwao.
Afiliación
  • Yan S; Department of Chemistry, Stony Brook University, Stony Brook, NY, 11794-3400, United states.
  • Elmes MW; Departments of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, 11794-5215, United states.
  • Tong S; Department of Chemistry, Stony Brook University, Stony Brook, NY, 11794-3400, United states.
  • Hu K; Institute of Chemical Biology and Drug Discovery, Stony Brook University, Stony Brook, NY, 11794-3400, United states.
  • Awwa M; Department of Chemistry, Stony Brook University, Stony Brook, NY, 11794-3400, United states.
  • Teng GYH; Institute of Chemical Biology and Drug Discovery, Stony Brook University, Stony Brook, NY, 11794-3400, United states.
  • Jing Y; Institute of Chemical Biology and Drug Discovery, Stony Brook University, Stony Brook, NY, 11794-3400, United states.
  • Freitag M; Department of Chemistry, Stony Brook University, Stony Brook, NY, 11794-3400, United states.
  • Gan Q; Department of Chemistry, Stony Brook University, Stony Brook, NY, 11794-3400, United states.
  • Clement T; Department of Chemistry, Stony Brook University, Stony Brook, NY, 11794-3400, United states.
  • Wei L; Department of Chemistry, Stony Brook University, Stony Brook, NY, 11794-3400, United states.
  • Sweeney JM; Departments of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, 11794-5215, United states.
  • Joseph OM; Departments of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, 11794-5215, United states.
  • Che J; Departments of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, 11794-5215, United states.
  • Carbonetti GS; Departments of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, 11794-5215, United states.
  • Wang L; Departments of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, 11794-5215, United states.
  • Bogdan DM; Department of Anesthesiology, Stony Brook University, Stony Brook, NY, 11794-8480, United states.
  • Falcone J; Department of Anesthesiology, Stony Brook University, Stony Brook, NY, 11794-8480, United states.
  • Smietalo N; Department of Anesthesiology, Stony Brook University, Stony Brook, NY, 11794-8480, United states.
  • Zhou Y; Applied Mathematics and Statistics, Stony Brook University, Stony Brook, NY, 11794-3600, United states.
  • Ralph B; Applied Mathematics and Statistics, Stony Brook University, Stony Brook, NY, 11794-3600, United states.
  • Hsu HC; Cryo-EM Structural Biology Laboratory, Van Andel Research Institute, Grand Rapids, MI, 49503, United states.
  • Li H; Cryo-EM Structural Biology Laboratory, Van Andel Research Institute, Grand Rapids, MI, 49503, United states.
  • Rizzo RC; Applied Mathematics and Statistics, Stony Brook University, Stony Brook, NY, 11794-3600, United states; Institute of Chemical Biology and Drug Discovery, Stony Brook University, Stony Brook, NY, 11794-3400, United states.
  • Deutsch DG; Departments of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, 11794-5215, United states; Institute of Chemical Biology and Drug Discovery, Stony Brook University, Stony Brook, NY, 11794-3400, United states.
  • Kaczocha M; Departments of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, 11794-5215, United states; Department of Anesthesiology, Stony Brook University, Stony Brook, NY, 11794-8480, United states; Institute of Chemical Biology and Drug Discovery, Stony Brook University, Stony Brook, N
  • Ojima I; Department of Chemistry, Stony Brook University, Stony Brook, NY, 11794-3400, United states; Institute of Chemical Biology and Drug Discovery, Stony Brook University, Stony Brook, NY, 11794-3400, United states. Electronic address: iwao.ojima@stonybrook.edu.
Eur J Med Chem ; 154: 233-252, 2018 Jun 25.
Article en En | MEDLINE | ID: mdl-29803996
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ciclobutanos / Ésteres / Proteínas de Unión a Ácidos Grasos / Analgésicos Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Eur J Med Chem Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ciclobutanos / Ésteres / Proteínas de Unión a Ácidos Grasos / Analgésicos Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Eur J Med Chem Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos