Downstream Products are Potent Inhibitors of the Heparan Sulfate 2-O-Sulfotransferase.

Thieker, David F; Xu, Yongmei; Chapla, Digantkumar; Nora, Chelsea; Qiu, Hong; Felix, Thomas; Wang, Lianchun; Moremen, Kelley W; Liu, Jian; Esko, Jeffrey D; Woods, Robert J

Thieker, David F; Xu, Yongmei; Chapla, Digantkumar; Nora, Chelsea; Qiu, Hong; Felix, Thomas; Wang, Lianchun; Moremen, Kelley W; Liu, Jian; Esko, Jeffrey D; Woods, Robert J.

Afiliación

Thieker DF; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, 30602, USA.
Xu Y; Complex Carbohydrate Research Center, University of Georgia, Athens, GA, 30602, USA.
Chapla D; Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Rm 1044, Genetic Medicine Building, Chapel Hill, USA.
Nora C; Complex Carbohydrate Research Center, University of Georgia, Athens, GA, 30602, USA.
Qiu H; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, USA.
Felix T; Complex Carbohydrate Research Center, University of Georgia, Athens, GA, 30602, USA.
Wang L; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, 30602, USA.
Moremen KW; Complex Carbohydrate Research Center, University of Georgia, Athens, GA, 30602, USA.
Liu J; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, 30602, USA.
Esko JD; Complex Carbohydrate Research Center, University of Georgia, Athens, GA, 30602, USA.
Woods RJ; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, 30602, USA.

Sci Rep ; 8(1): 11832, 2018 08 07.

Article en En | MEDLINE | ID: mdl-30087361

Asunto(s)

Heparitina Sulfato/biosíntesis; Oligosacáridos/metabolismo; Sulfatos/metabolismo; Sulfotransferasas/metabolismo; Animales; Sitios de Unión/genética; Unión Competitiva; Células CHO; Línea Celular; Cricetinae; Cricetulus; Glucosamina/química; Glucosamina/metabolismo; Heparitina Sulfato/química; Heparitina Sulfato/metabolismo; Humanos; Simulación del Acoplamiento Molecular; Mutación; Oligosacáridos/química; Especificidad por Sustrato; Sulfatos/química; Sulfotransferasas/química; Sulfotransferasas/genética

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Oligosacáridos / Sulfatos / Sulfotransferasas / Heparitina Sulfato Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google