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Phase 1 Single- and Multiple-Ascending-Dose Randomized Studies of the Safety, Pharmacokinetics, and Pharmacodynamics of AG-348, a First-in-Class Allosteric Activator of Pyruvate Kinase R, in Healthy Volunteers.
Yang, Hua; Merica, Elizabeth; Chen, Yue; Cohen, Marvin; Goldwater, Ronald; Kosinski, Penelope A; Kung, Charles; Yuan, Zheng Jason; Silverman, Lee; Goldwasser, Meredith; Silver, Bruce A; Agresta, Sam; Barbier, Ann J.
Afiliación
  • Yang H; Agios Pharmaceuticals, Inc., Cambridge, MA, USA.
  • Merica E; Agios Pharmaceuticals, Inc., Cambridge, MA, USA.
  • Chen Y; Agios Pharmaceuticals, Inc., Cambridge, MA, USA.
  • Cohen M; MBC Pharma Solutions, Newtown, PA, USA.
  • Goldwater R; PAREXEL International, Baltimore, MD, USA.
  • Kosinski PA; Agios Pharmaceuticals, Inc., Cambridge, MA, USA.
  • Kung C; Agios Pharmaceuticals, Inc., Cambridge, MA, USA.
  • Yuan ZJ; Agios Pharmaceuticals, Inc., Cambridge, MA, USA.
  • Silverman L; Agios Pharmaceuticals, Inc., Cambridge, MA, USA.
  • Goldwasser M; Agios Pharmaceuticals, Inc., Cambridge, MA, USA.
  • Silver BA; Bruce A Silver Clinical Science and Development, Dunkirk, MD, USA.
  • Agresta S; Agios Pharmaceuticals, Inc., Cambridge, MA, USA.
  • Barbier AJ; Agios Pharmaceuticals, Inc., Cambridge, MA, USA.
Clin Pharmacol Drug Dev ; 8(2): 246-259, 2019 02.
Article en En | MEDLINE | ID: mdl-30091852
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piperazinas / Quinolinas Tipo de estudio: Clinical_trials Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Pharmacol Drug Dev Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piperazinas / Quinolinas Tipo de estudio: Clinical_trials Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Pharmacol Drug Dev Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos