Overexpression of Grainyhead-like 3 causes spina bifida and interacts genetically with mutant alleles of Grhl2 and Vangl2 in mice.

De Castro, Sandra C P; Gustavsson, Peter; Marshall, Abigail R; Gordon, William M; Galea, Gabriel; Nikolopoulou, Evanthia; Savery, Dawn; Rolo, Ana; Stanier, Philip; Andersen, Bogi; Copp, Andrew J; Greene, Nicholas D E

De Castro, Sandra C P; Gustavsson, Peter; Marshall, Abigail R; Gordon, William M; Galea, Gabriel; Nikolopoulou, Evanthia; Savery, Dawn; Rolo, Ana; Stanier, Philip; Andersen, Bogi; Copp, Andrew J; Greene, Nicholas D E.

Afiliación

De Castro SCP; Developmental Biology & Cancer Programme, UCL Great Ormond Street Institute of Child Health, University College London, London, UK.
Gustavsson P; Developmental Biology & Cancer Programme, UCL Great Ormond Street Institute of Child Health, University College London, London, UK.
Marshall AR; Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden.
Gordon WM; Developmental Biology & Cancer Programme, UCL Great Ormond Street Institute of Child Health, University College London, London, UK.
Galea G; Department of Biological Chemistry, University of California Irvine, Irvine, California, USA.
Nikolopoulou E; Developmental Biology & Cancer Programme, UCL Great Ormond Street Institute of Child Health, University College London, London, UK.
Savery D; Developmental Biology & Cancer Programme, UCL Great Ormond Street Institute of Child Health, University College London, London, UK.
Rolo A; Developmental Biology & Cancer Programme, UCL Great Ormond Street Institute of Child Health, University College London, London, UK.
Stanier P; Developmental Biology & Cancer Programme, UCL Great Ormond Street Institute of Child Health, University College London, London, UK.
Andersen B; Genetics and Genomic Medicine Programme, UCL Great Ormond Street Institute of Child Health, University College London, London, UK.
Copp AJ; Department of Biological Chemistry, University of California Irvine, Irvine, California, USA.
Greene NDE; Department of Medicine, School of Medicine, University of California Irvine, Irvine, California, USA.

Hum Mol Genet ; 27(24): 4218-4230, 2018 12 15.

Article en En | MEDLINE | ID: mdl-30189017

Asunto(s)

Proteínas de Unión al ADN/genética; Proteínas del Tejido Nervioso/genética; Defectos del Tubo Neural/genética; Disrafia Espinal/genética; Factores de Transcripción/genética; Alelos; Animales; Animales Modificados Genéticamente/genética; Modelos Animales de Enfermedad; Desarrollo Embrionario/genética; Regulación del Desarrollo de la Expresión Génica/genética; Humanos; Mutación con Pérdida de Función; Ratones; Defectos del Tubo Neural/patología; Multimerización de Proteína/genética; Disrafia Espinal/patología

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Disrafia Espinal / Proteínas de Unión al ADN / Proteínas del Tejido Nervioso / Defectos del Tubo Neural Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google