Molecular evolutionary and antigenic characteristics of newly isolated H9N2 avian influenza viruses in Guangdong province, China.
Arch Virol
; 164(2): 607-612, 2019 Feb.
Article
en En
| MEDLINE
| ID: mdl-30474753
ABSTRACT
Four new H9N2 avian influenza viruses (AIVs) were isolated from domestic birds in Guangdong between December 2015 and April 2016. Nucleotide sequence comparisons indicated that most of the internal genes of these four strains were highly similar to those of human H7N9 viruses. Amino acid substitutions and deletions found in the HA and NA proteins indicated that all four of these new isolates may have an enhanced ability to infect humans and other mammals. A cross-hemagglutinin-inhibition assay, conducted with two vaccine strains that are broadly used in China, suggested that antisera against vaccine candidates could not provide complete inhibition of the new isolates.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Enfermedades de las Aves de Corral
/
Evolución Molecular
/
Subtipo H9N2 del Virus de la Influenza A
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Gripe Aviar
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Antígenos Virales
Límite:
Animals
/
Humans
País/Región como asunto:
Asia
Idioma:
En
Revista:
Arch Virol
Año:
2019
Tipo del documento:
Article