Antibody responses to malarial antigens in the Wopkaimin population of the Star Mountains, Papua New Guinea.
Am J Trop Med Hyg
; 39(3): 241-5, 1988 Sep.
Article
en En
| MEDLINE
| ID: mdl-3052119
ABSTRACT
Antibody responses to malarial antigens were determined in 614 serum samples collected from the Wopkaimin population of the Star Mountains of Papua New Guinea. In point prevalence surveys made in 1982-1983, 33.7% of the persons examined were infected with Plasmodium falciparum, P. vivax, or P. malariae. Of these, 72.9% were infected with P. falciparum. In a standard fluorescent antibody test, highest level responses were to P. falciparum, followed by P. malariae, P. vivax, and P. ovale. A strong correlation was found between results of the fluorescent antibody tests and those obtained in an enzyme-linked immunosorbent assay using P. falciparum antigens. The failure of immune responses to eliminate these species of Plasmodium in this highly isolated population is discussed.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Plasmodium
/
Anticuerpos Antiprotozoarios
/
Malaria
/
Antígenos de Protozoos
Tipo de estudio:
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Animals
/
Child
/
Child, preschool
/
Humans
Idioma:
En
Revista:
Am J Trop Med Hyg
Año:
1988
Tipo del documento:
Article
País de afiliación:
Georgia