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A genome-wide RNAi screen identifies the SMC5/6 complex as a non-redundant regulator of a Topo2a-dependent G2 arrest.
Deiss, Katharina; Lockwood, Nicola; Howell, Michael; Segeren, Hendrika Alida; Saunders, Rebecca E; Chakravarty, Probir; Soliman, Tanya N; Martini, Silvia; Rocha, Nuno; Semple, Robert; Zalmas, Lykourgos-Panagiotis; Parker, Peter J.
Afiliación
  • Deiss K; Protein Phosphorylation Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Lockwood N; Protein Phosphorylation Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Howell M; High Throughput Screening, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Segeren HA; Protein Phosphorylation Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Saunders RE; High Throughput Screening, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Chakravarty P; Bioinformatics, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Soliman TN; Protein Phosphorylation Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Martini S; Protein Phosphorylation Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Rocha N; The University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Cambridge CB2 0QQ, UK.
  • Semple R; The National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge CB2 0QQ, UK.
  • Zalmas LP; Translational Cancer Therapeutics, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
  • Parker PJ; Protein Phosphorylation Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
Nucleic Acids Res ; 47(6): 2906-2921, 2019 04 08.
Article en En | MEDLINE | ID: mdl-30590722

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: ADN-Topoisomerasas de Tipo II / Sumoilación / Puntos de Control de la Fase G2 del Ciclo Celular / Proteínas de Unión a Poli-ADP-Ribosa / Ligasas Límite: Humans Idioma: En Revista: Nucleic Acids Res Año: 2019 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: ADN-Topoisomerasas de Tipo II / Sumoilación / Puntos de Control de la Fase G2 del Ciclo Celular / Proteínas de Unión a Poli-ADP-Ribosa / Ligasas Límite: Humans Idioma: En Revista: Nucleic Acids Res Año: 2019 Tipo del documento: Article País de afiliación: Reino Unido