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Research on association between variants and haplotypes of TRPV1 and TRPA1 genes with growth traits in three cattle breeds.
Wu, Jiyao; Wang, Jianjin; Yue, Binglin; Xing-Tang, Fang; Zhang, Chunlei; Ma, Yun; Hu, Linyong; Bai, Yueyu; Qi, Xingshan; Chen, Hong.
Afiliación
  • Wu J; a Institute of Cellular and Molecular Biology, School of Life Science, Jiangsu Normal University , Xuzhou , PR China.
  • Wang J; a Institute of Cellular and Molecular Biology, School of Life Science, Jiangsu Normal University , Xuzhou , PR China.
  • Yue B; a Institute of Cellular and Molecular Biology, School of Life Science, Jiangsu Normal University , Xuzhou , PR China.
  • Xing-Tang F; a Institute of Cellular and Molecular Biology, School of Life Science, Jiangsu Normal University , Xuzhou , PR China.
  • Zhang C; a Institute of Cellular and Molecular Biology, School of Life Science, Jiangsu Normal University , Xuzhou , PR China.
  • Ma Y; b College of Life Sciences , Institute for Conservation and Utilization of Agro-Bioresources in Dabie Mountains, Xinyang Normal University , Xinyang , PR China.
  • Hu L; c Key Laboratory of Adaptation and Evolution of Plateau Biota , Northwest Institute of Plateau Biology, Chinese Academy of Sciences , Xining , PR China.
  • Bai Y; d Animal Health Supervision in Henan Province , Zhengzhou , PR China.
  • Qi X; e Bureau of Animal Husbandry of Biyang County , Biyang , PR China.
  • Chen H; e Bureau of Animal Husbandry of Biyang County , Biyang , PR China.
Anim Biotechnol ; 30(3): 202-211, 2019 Jul.
Article en En | MEDLINE | ID: mdl-30595081
ABSTRACT
The objective of this study was to examine the association of transient receptor potential vanilloid 1 (TRPV1) and transient receptor potential ankyrin 1 (TRPA1) genes polymorphisms with growth traits in three Chinese cattle breeds (Jiaxian red cattle, Qinchuan cattle and Luxi cattle). Through experiments we identified three single nucleotide polymorphisms (SNPs) in these three cattle breeds TRPV1 and TRPA1 genes using PCR-SSCP, (forced) PCR-RFLP methods. Three of these polymorphisms are all synonymous mutation which includes (NW_003104493.1 30327 C > T), (NW_003104493.1 33394 A > G) and (NW_003104493.1 38471 G > A) are in exons. The other three polymorphisms are located at 3'UTR. Furthermore, we evaluated the haplotype frequency and the statistical analyses indicated that these SNPs of TRPV1 and TRPA1 genes were associated with bovine body height, body length, waist angle width, hucklebone width, cross ministry height, chest qingwidth (p < 0.05) and recommendation height, cannon circumference (p < 0.01) of Qingchuan cattle; body length, waist angle width (p < 0.05) of Jiaxian red cattle; body weight, Body length, cannon circumference, chest circumference (p < 0.05) and body height (p < 0.01) of Luxi cattle. Our result confirms the polymorphisms in the TRPV1 and TRPA1 genes are associated with growth traits that may be used for marker-assisted selection (MAS) in three beef breeds programs.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Variación Genética / Bovinos / Canales Catiónicos TRPV / Canal Catiónico TRPA1 Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Anim Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2019 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Variación Genética / Bovinos / Canales Catiónicos TRPV / Canal Catiónico TRPA1 Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Anim Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2019 Tipo del documento: Article