BMP-dependent, injury-induced stem cell niche as a mechanism of heterotopic ossification.

Kan, Chen; Ding, Na; Yang, Jiazhao; Tan, Zhenya; McGuire, Tammy L; Lu, Haimei; Zhang, Keqin; Berger, Diana M Palila; Kessler, John A; Kan, Lixin

Kan, Chen; Ding, Na; Yang, Jiazhao; Tan, Zhenya; McGuire, Tammy L; Lu, Haimei; Zhang, Keqin; Berger, Diana M Palila; Kessler, John A; Kan, Lixin.

Afiliación

Kan C; School of Basic Medical Sciences, Anhui Medical University, 81 Meishan road, Hefei, 230032, China.
Ding N; School of Basic Medical Sciences, Anhui Medical University, 81 Meishan road, Hefei, 230032, China.
Yang J; Department of Traumatic Orthopedics, Anhui Provincial Hospital, The first Affiliated Hospital of China University of Science and Technology, Hefei, 233000, China.
Tan Z; School of Basic Medical Sciences, Anhui Medical University, 81 Meishan road, Hefei, 230032, China.
McGuire TL; Department of Neurology, Northwestern University, Ward Building 10-233, 303 East Chicago Avenue, Chicago, IL, 60611-3008, USA.
Lu H; School of Basic Medical Sciences, Anhui Medical University, 81 Meishan road, Hefei, 230032, China.
Zhang K; Department of Endocrinology and Metabolism, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Berger DMP; Center for Comparative Medicine, Northwestern University Feinberg Medical School, Chicago, IL, 60611-3008, USA.
Kessler JA; Department of Neurology, Northwestern University, Ward Building 10-233, 303 East Chicago Avenue, Chicago, IL, 60611-3008, USA.
Kan L; School of Basic Medical Sciences, Anhui Medical University, 81 Meishan road, Hefei, 230032, China. l-kan@northwestern.edu.

Stem Cell Res Ther ; 10(1): 14, 2019 01 11.

Article en En | MEDLINE | ID: mdl-30635039

Asunto(s)

Miositis Osificante/genética; Osificación Heterotópica/genética; Osteogénesis/genética; Nicho de Células Madre/genética; Animales; Diferenciación Celular/genética; Proliferación Celular/genética; Toxina Diftérica/genética; Modelos Animales de Enfermedad; Transportador 1 de Aminoácidos Excitadores/genética; Humanos; Mutación con Pérdida de Función/genética; Células Madre Mesenquimatosas/citología; Células Madre Mesenquimatosas/metabolismo; Ratones; Miositis Osificante/patología; Miositis Osificante/terapia; Osificación Heterotópica/patología; Osificación Heterotópica/terapia; Fragmentos de Péptidos/genética; Receptor TIE-2/genética; Transducción de Señal/genética; Proteína con Dedos de Zinc GLI1/genética

Palabras clave

Bone morphogenetic protein (BMP); Hedgehog (Hh); Heterotopic ossification (HO); Mesenchymal stem cells (MSCs); Niche; Niche supportive cells; Niche supportive molecules

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Osteogénesis / Osificación Heterotópica / Nicho de Células Madre / Miositis Osificante Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Stem Cell Res Ther Año: 2019 Tipo del documento: Article País de afiliación: China

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