Your browser doesn't support javascript.
loading
Pituitary dysfunction due to sports-related traumatic brain injury.
Hacioglu, Aysa; Kelestimur, Fahrettin; Tanriverdi, Fatih.
Afiliación
  • Hacioglu A; Department of Endocrinology and Metabolism, Erciyes University Medical School, Kayseri, Turkey. aysahadzalic@gmail.com.
  • Kelestimur F; Yeditepe University Medical Faculty, Istanbul, Turkey.
  • Tanriverdi F; Memorial Kayseri Hospital, Endocrinology Clinic, Kayseri, Turkey.
Pituitary ; 22(3): 322-331, 2019 Jun.
Article en En | MEDLINE | ID: mdl-30637622
ABSTRACT

PURPOSE:

After traumatic brain injury was accepted as an important etiologic factor of pituitary dysfunction (PD), awareness of risk of developing PD following sports-related traumatic brain injury (SR-TBI) has also increased. However there are not many studies investigating PD following SR-TBIs yet. We aimed to summarize the data reported so far and to discuss screening algorithms and treatment strategies.

METHODS:

Recent data on pituitary dysfunction after SR-TBIs is reviewed on basis of diagnosis, clinical perspectives, therapy, screening and possible prevention strategies.

RESULTS:

Pituitary dysfunction is reported to occur in a range of 15-46.6% following SR-TBIs depending on the study design. Growth hormone is the most commonly reported pituitary hormone deficiency in athletes. Pituitary hormone deficiencies may occur during acute phase after head trauma, may improve with time or new deficiencies may develop during follow-up. Central adrenal insufficiency is the only and most critical impairment that requires urgent detection and replacement during acute phase. Decision on replacement of growth hormone and gonadal deficiencies should be individualized. Moreover these two hormones are abused by many athletes and a therapeutic use exemption from the league's drug policy may be required.

CONCLUSIONS:

Even mild and forgotten SR-TBIs may cause PD that may have distressing consequences in some cases if remain undiagnosed. More studies are needed to elucidate epidemiology and pathophysiology of PD after SR-TBIs. Also studies to establish screening algorithms for PD as well as strategies for prevention of SR-TBIs are urgently required.
Asunto(s)
Palabras clave

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Hipófisis / Traumatismos en Atletas / Lesiones Traumáticas del Encéfalo Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Pituitary Asunto de la revista: ENDOCRINOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Turquía

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Hipófisis / Traumatismos en Atletas / Lesiones Traumáticas del Encéfalo Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Pituitary Asunto de la revista: ENDOCRINOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Turquía