Clinical Response to Induction Chemotherapy Predicts Outcome after Combined-Modality Therapy in Inflammatory Breast Cancer.
Cancer Invest
; 37(1): 29-38, 2019.
Article
en En
| MEDLINE
| ID: mdl-30656969
ABSTRACT
PURPOSE:
To assess predictors of outcome in a cohort of Inflammatory Breast Cancer (IBC) patients receiving induction chemotherapy followed by local treatment.METHODS:
We retrospectively reviewed 95 non-metastatic IBC patient files.RESULTS:
Complete clinical response (cCR) was obtained in 15 (16%) patients. Median follow up was 13.4 years (IC95% 10.4-14.6). Loco-regional control (LC), disease-free survival (DFS), and overall survival (OS) at 5 years were 85%, 41%, and 55%, respectively; cCR was associated with better DFS and OS in multivariate analyses adjusted for age (p = 0.02).CONCLUSIONS:
Clinical response to upfront chemotherapy predicts the outcome of patients affected by IBC.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Terapia Combinada
/
Neoplasias Inflamatorias de la Mama
/
Quimioterapia de Inducción
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Cancer Invest
Año:
2019
Tipo del documento:
Article
País de afiliación:
Francia