Generation of insulin-producing hepatocyte-like cells from human Wharton's jelly mesenchymal stem cells as an alternative source of islet cells.

Beikmohammadi, Leila; Bandehpour, Mojgan; Hashemi, Seyed Mahmoud; Kazemi, Bahram

Beikmohammadi, Leila; Bandehpour, Mojgan; Hashemi, Seyed Mahmoud; Kazemi, Bahram.

Afiliación

Beikmohammadi L; Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Bandehpour M; Cellular and Molecular Biology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Hashemi SM; Cellular and Molecular Biology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Kazemi B; Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

J Cell Physiol ; 234(10): 17326-17336, 2019 08.

Article en En | MEDLINE | ID: mdl-30790280

Asunto(s)

Insulina/metabolismo; Islotes Pancreáticos/metabolismo; Células Madre Mesenquimatosas/metabolismo; Gelatina de Wharton/citología; Animales; Diferenciación Celular/fisiología; Células Cultivadas; Glucosa/metabolismo; Hepatocitos/metabolismo; Humanos; Células Secretoras de Insulina/metabolismo; Ratas

Palabras clave

Wharton's jelly mesenchymal stem cells; cell therapy; glucose-responsive elements; insulin-producing hepatocyte-like cells; type 1 diabetes

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Islotes Pancreáticos / Gelatina de Wharton / Células Madre Mesenquimatosas / Insulina Límite: Animals / Humans Idioma: En Revista: J Cell Physiol Año: 2019 Tipo del documento: Article País de afiliación: Irán

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