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Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects.
Ooi, Jolene; Langley, Sarah R; Xu, Xiaohong; Utami, Kagistia H; Sim, Bernice; Huang, Yihui; Harmston, Nathan P; Tay, Yi Lin; Ziaei, Amin; Zeng, Ruizhu; Low, Donovan; Aminkeng, Folefac; Sobota, Radoslaw M; Ginhoux, Florent; Petretto, Enrico; Pouladi, Mahmoud A.
Afiliación
  • Ooi J; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A(∗)STAR), Singapore 138648, Singapore.
  • Langley SR; Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore.
  • Xu X; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A(∗)STAR), Singapore 138648, Singapore; Department of Neurology and Stroke Center, The First Affiliated Hospital, Jinan University, 613 Huangpu Avenue West, Guangzhou, Guangdong 510632, China; Cli
  • Utami KH; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A(∗)STAR), Singapore 138648, Singapore.
  • Sim B; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A(∗)STAR), Singapore 138648, Singapore.
  • Huang Y; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A(∗)STAR), Singapore 138648, Singapore.
  • Harmston NP; Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.
  • Tay YL; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A(∗)STAR), Singapore 138648, Singapore.
  • Ziaei A; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A(∗)STAR), Singapore 138648, Singapore.
  • Zeng R; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A(∗)STAR), Singapore 138648, Singapore.
  • Low D; Singapore Immunology Network (SIgN), A(∗)STAR, Singapore 138648, Singapore.
  • Aminkeng F; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A(∗)STAR), Singapore 138648, Singapore.
  • Sobota RM; Functional Proteomics Laboratory, Institute of Molecular and Cell Biology (IMCB), A(∗)STAR, Singapore 138648, Singapore; Institute of Medical Biology (IMB), A(∗)STAR, Singapore 138648, Singapore.
  • Ginhoux F; Singapore Immunology Network (SIgN), A(∗)STAR, Singapore 138648, Singapore.
  • Petretto E; Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.
  • Pouladi MA; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A(∗)STAR), Singapore 138648, Singapore; Department of Medicine, National University of Singapore (NUS), Singapore 117597, Singapore; Department of Physiology, National University of Singapore (NUS
Cell Rep ; 26(9): 2494-2508.e7, 2019 02 26.
Article en En | MEDLINE | ID: mdl-30811996
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedad de Huntington / Repeticiones de Trinucleótidos / Células Madre Embrionarias / Proteína Huntingtina Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Cell Rep Año: 2019 Tipo del documento: Article País de afiliación: Singapur
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedad de Huntington / Repeticiones de Trinucleótidos / Células Madre Embrionarias / Proteína Huntingtina Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Cell Rep Año: 2019 Tipo del documento: Article País de afiliación: Singapur