Pharmacokinetics and toxicity of high-dose baclofen in ICU patients.

Vourc'h, Mickael; Dailly, Eric; Hourmant, Yannick; Bellouard, Ronan; Mahe, Pierre-Joachim; Deslandes, Guillaume; Grégoire, Matthieu; Asehnoune, Karim

Vourc'h, Mickael; Dailly, Eric; Hourmant, Yannick; Bellouard, Ronan; Mahe, Pierre-Joachim; Deslandes, Guillaume; Grégoire, Matthieu; Asehnoune, Karim.

Afiliación

Vourc'h M; Departments of Anesthesiology and Surgical Intensive Care, Hôtel-Dieu, University Hospital of Nantes, Nantes, France.
Dailly E; Clinical Pharmacology Department, University Hospital of Nantes, Nantes, France.
Hourmant Y; Departments of Anesthesiology and Surgical Intensive Care, Hôtel-Dieu, University Hospital of Nantes, Nantes, France.
Bellouard R; Clinical Pharmacology Department, University Hospital of Nantes, Nantes, France.
Mahe PJ; Departments of Anesthesiology and Surgical Intensive Care, Hôtel-Dieu, University Hospital of Nantes, Nantes, France.
Deslandes G; Clinical Pharmacology Department, University Hospital of Nantes, Nantes, France.
Grégoire M; Clinical Pharmacology Department, University Hospital of Nantes, Nantes, France.
Asehnoune K; Departments of Anesthesiology and Surgical Intensive Care, Hôtel-Dieu, University Hospital of Nantes, Nantes, France; Department of Anesthesiology and Surgical Intensive Care, Hôtel-Dieu, University Hospital of Nantes, 44093 Nantes, France. Electronic address: karim.asehnoune@chu-nantes.fr.

Prog Neuropsychopharmacol Biol Psychiatry ; 92: 450-456, 2019 06 08.

Article en En | MEDLINE | ID: mdl-30826461

Asunto(s)

Alcoholismo/sangre; Baclofeno/efectos adversos; Baclofeno/farmacocinética; Cuidados Críticos/métodos; Unidades de Cuidados Intensivos; Alcoholismo/complicaciones; Alcoholismo/fisiopatología; Baclofeno/administración & dosificación; Baclofeno/sangre; Tasa de Filtración Glomerular/fisiología; Humanos; Masculino; Persona de Mediana Edad; Dinámicas no Lineales; Insuficiencia Renal/sangre; Insuficiencia Renal/complicaciones

Palabras clave

Agitation-related adverse events; Alcohol use disorders; Alcohol withdrawal syndrome; Baclofen; Intensive care unit; Pharmacokinetics

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Baclofeno / Cuidados Críticos / Alcoholismo / Unidades de Cuidados Intensivos Límite: Humans / Male / Middle aged Idioma: En Revista: Prog Neuropsychopharmacol Biol Psychiatry Año: 2019 Tipo del documento: Article País de afiliación: Francia

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