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Treatment of primary Sjögren's syndrome with ianalumab (VAY736) targeting B cells by BAFF receptor blockade coupled with enhanced, antibody-dependent cellular cytotoxicity.
Dörner, Thomas; Posch, Maximilian Georg; Li, Yue; Petricoul, Olivier; Cabanski, Maciej; Milojevic, Julie Marie; Kamphausen, Esther; Valentin, Marie-Anne; Simonett, Claudia; Mooney, Louise; Hüser, Andreas; Gram, Hermann; Wagner, Frank Dietrich; Oliver, Stephen John.
Afiliación
  • Dörner T; Department of Medicine, Rheumatology and Clinical Immunology, Charite University Hospital, Berlin, Germany.
  • Posch MG; Charité Research Organisation GmbH, Berlin, Germany.
  • Li Y; Integrated Information Sciences, Novartis Pharma, Basel, Switzerland.
  • Petricoul O; Translational Medicine, Novartis Pharma, Basel, Switzerland.
  • Cabanski M; Autoimmunity, Transplant and Inflammation, Novartis Pharma, Basel, Switzerland.
  • Milojevic JM; Translational Medicine, Novartis Pharma, Basel, Switzerland.
  • Kamphausen E; Translational Medicine, Novartis Pharma, Basel, Switzerland.
  • Valentin MA; Translational Medicine, Novartis Pharma, Basel, Switzerland.
  • Simonett C; Translational Medicine, Novartis Pharma, Basel, Switzerland.
  • Mooney L; Translational Medicine, Novartis Pharma, Basel, Switzerland.
  • Hüser A; Charité Research Organisation GmbH, Berlin, Germany.
  • Gram H; Autoimmunity, Transplant and Inflammation, Novartis Pharma, Basel, Switzerland.
  • Wagner FD; Charité Research Organisation GmbH, Berlin, Germany.
  • Oliver SJ; Translational Medicine, Novartis Pharma, Basel, Switzerland stephen.oliver@novartis.com.
Ann Rheum Dis ; 78(5): 641-647, 2019 05.
Article en En | MEDLINE | ID: mdl-30826774
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfocitos B / Síndrome de Sjögren / Receptor del Factor Activador de Células B / Anticuerpos Monoclonales Humanizados / Anticuerpos Monoclonales / Citotoxicidad Celular Dependiente de Anticuerpos Tipo de estudio: Clinical_trials / Etiology_studies Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Rheum Dis Año: 2019 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfocitos B / Síndrome de Sjögren / Receptor del Factor Activador de Células B / Anticuerpos Monoclonales Humanizados / Anticuerpos Monoclonales / Citotoxicidad Celular Dependiente de Anticuerpos Tipo de estudio: Clinical_trials / Etiology_studies Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Rheum Dis Año: 2019 Tipo del documento: Article País de afiliación: Alemania