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Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials.
Dodean, Rozalia A; Kancharla, Papireddy; Li, Yuexin; Melendez, Victor; Read, Lisa; Bane, Charles E; Vesely, Brian; Kreishman-Deitrick, Mara; Black, Chad; Li, Qigui; Sciotti, Richard J; Olmeda, Raul; Luong, Thu-Lan; Gaona, Heather; Potter, Brittney; Sousa, Jason; Marcsisin, Sean; Caridha, Diana; Xie, Lisa; Vuong, Chau; Zeng, Qiang; Zhang, Jing; Zhang, Ping; Lin, Hsiuling; Butler, Kirk; Roncal, Norma; Gaynor-Ohnstad, Lacy; Leed, Susan E; Nolan, Christina; Huezo, Stephanie J; Rasmussen, Stephanie A; Stephens, Melissa T; Tan, John C; Cooper, Roland A; Smilkstein, Martin J; Pou, Sovitj; Winter, Rolf W; Riscoe, Michael K; Kelly, Jane X.
Afiliación
  • Dodean RA; Department of Chemistry , Portland State University , Portland , Oregon 97201 , United States.
  • Kancharla P; Department of Veterans Affairs Medical Center , Portland , Oregon 97239 , United States.
  • Li Y; Department of Chemistry , Portland State University , Portland , Oregon 97201 , United States.
  • Melendez V; Department of Chemistry , Portland State University , Portland , Oregon 97201 , United States.
  • Read L; Department of Veterans Affairs Medical Center , Portland , Oregon 97239 , United States.
  • Bane CE; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Vesely B; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Kreishman-Deitrick M; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Black C; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Li Q; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Sciotti RJ; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Olmeda R; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Luong TL; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Gaona H; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Potter B; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Sousa J; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Marcsisin S; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Caridha D; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Xie L; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Vuong C; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Zeng Q; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Zhang J; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Zhang P; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Lin H; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Butler K; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Roncal N; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Gaynor-Ohnstad L; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Leed SE; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Nolan C; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Huezo SJ; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Rasmussen SA; Division of Experimental Therapeutics , Walter Reed Army Institute of Research , Silver Spring , Maryland 20910 , United States.
  • Stephens MT; Department of Natural Sciences and Mathematics , Dominican University of California , San Rafael , California 94901 , United States.
  • Tan JC; Department of Natural Sciences and Mathematics , Dominican University of California , San Rafael , California 94901 , United States.
  • Pou S; Department of Natural Sciences and Mathematics , Dominican University of California , San Rafael , California 94901 , United States.
  • Winter RW; Department of Veterans Affairs Medical Center , Portland , Oregon 97239 , United States.
  • Riscoe MK; Department of Veterans Affairs Medical Center , Portland , Oregon 97239 , United States.
  • Kelly JX; Department of Chemistry , Portland State University , Portland , Oregon 97201 , United States.
J Med Chem ; 62(7): 3475-3502, 2019 04 11.
Article en En | MEDLINE | ID: mdl-30852885
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Acridonas / Descubrimiento de Drogas / Antimaláricos Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Acridonas / Descubrimiento de Drogas / Antimaláricos Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos