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Blockage of ROS and MAPKs-mediated inflammation via restoring SIRT1 by a new compound LF10 prevents type 1 diabetic cardiomyopathy.
Luo, Wu; Jin, Yiyi; Wu, Gaojun; Zhu, Weiwei; Qian, Yuanyuan; Zhang, Yali; Li, Jieli; Zhu, Aisong; Liang, Guang.
Afiliación
  • Luo W; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Zhejiang, Wenzhou, China.
  • Jin Y; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Zhejiang, Wenzhou, China.
  • Wu G; Department of Cardiology, The First Affiliated Hospital, Wenzhou Medical University, Zhejiang, Wenzhou, China.
  • Zhu W; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Zhejiang, Wenzhou, China.
  • Qian Y; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Zhejiang, Wenzhou, China.
  • Zhang Y; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Zhejiang, Wenzhou, China.
  • Li J; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Zhejiang, Wenzhou, China.
  • Zhu A; School of Basic Medicine, Liaoning University of Traditional Chinese Medicine, Liaoning, Shenyang, China.
  • Liang G; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Zhejiang, Wenzhou, China. Electronic address: wzmcliangguang@163.com.
Toxicol Appl Pharmacol ; 370: 24-35, 2019 05 01.
Article en En | MEDLINE | ID: mdl-30857947
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Especies Reactivas de Oxígeno / Proteínas Quinasas Activadas por Mitógenos / Sirtuina 1 / Cardiomiopatías Diabéticas / Inflamación Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Toxicol Appl Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Especies Reactivas de Oxígeno / Proteínas Quinasas Activadas por Mitógenos / Sirtuina 1 / Cardiomiopatías Diabéticas / Inflamación Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Toxicol Appl Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: China