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A novel MyD88 inhibitor LM9 prevents atherosclerosis by regulating inflammatory responses and oxidative stress in macrophages.
Chen, Taiwei; Luo, Wu; Wu, Gaojun; Wu, Lanlan; Huang, Shushi; Li, Jieli; Wang, Jingying; Hu, Xiang; Huang, Weijian; Liang, Guang.
Afiliación
  • Chen T; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China; Department of Cardiology, the First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
  • Luo W; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
  • Wu G; Department of Cardiology, the First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
  • Wu L; Department of Pharmacy, Traditional Chinese Medicine Hospital of Yiwu, Yiwu, Zhejiang 322000, China.
  • Huang S; Department of Cardiology, the First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
  • Li J; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
  • Wang J; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
  • Hu X; Department of Endocrinology, the First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
  • Huang W; Department of Cardiology, the First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China. Electronic address: weijianhuang69@126.com.
  • Liang G; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China. Electronic address: wzmcliangguang@163.com.
Toxicol Appl Pharmacol ; 370: 44-55, 2019 05 01.
Article en En | MEDLINE | ID: mdl-30880215
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piperazinas / Tiazoles / Aterosclerosis / Factor 88 de Diferenciación Mieloide Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Toxicol Appl Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piperazinas / Tiazoles / Aterosclerosis / Factor 88 de Diferenciación Mieloide Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Toxicol Appl Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: China