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Molecular design opportunities presented by solvent-exposed regions of target proteins.
Jiang, Xiangyi; Yu, Ji; Zhou, Zhongxia; Kongsted, Jacob; Song, Yuning; Pannecouque, Christophe; De Clercq, Erik; Kang, Dongwei; Poongavanam, Vasanthanathan; Liu, Xinyong; Zhan, Peng.
Afiliación
  • Jiang X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, People's Republic of China.
  • Yu J; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, People's Republic of China.
  • Zhou Z; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, People's Republic of China.
  • Kongsted J; Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Odense, Denmark.
  • Song Y; Department of Clinical Pharmacy, Qilu Hospital of Shandong University, Jinan, China.
  • Pannecouque C; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
  • De Clercq E; Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
  • Kang D; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, People's Republic of China.
  • Poongavanam V; Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Odense, Denmark.
  • Liu X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, People's Republic of China.
  • Zhan P; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, People's Republic of China.
Med Res Rev ; 39(6): 2194-2238, 2019 11.
Article en En | MEDLINE | ID: mdl-31002405
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Solventes / Diseño de Fármacos / Proteínas Idioma: En Revista: Med Res Rev Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Solventes / Diseño de Fármacos / Proteínas Idioma: En Revista: Med Res Rev Año: 2019 Tipo del documento: Article