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Tolvaptan use in children and adolescents with autosomal dominant polycystic kidney disease: rationale and design of a two-part, randomized, double-blind, placebo-controlled trial.
Schaefer, Franz; Mekahli, Djalila; Emma, Francesco; Gilbert, Rodney D; Bockenhauer, Detlef; Cadnapaphornchai, Melissa A; Shi, Lily; Dandurand, Ann; Sikes, Kimberly; Shoaf, Susan E.
Afiliación
  • Schaefer F; Division of Pediatric Nephrology, University Children's Hospital Heidelberg, Im Neuenheimer Feld 430, 69120, Heidelberg, Germany. Franz.Schaefer@med.uni-heidelberg.de.
  • Mekahli D; Department of Pediatric Nephrology, University Hospitals Leuven, Herestraat 49, B-3000, Leuven, Belgium.
  • Emma F; PKD Research Group, Department of Development and Regeneration, KU Leuven, Herestraat 49, B-3000, Leuven, Belgium.
  • Gilbert RD; Pediatric Nephrology, Bambino Gesù Children's Hospital, Piazza Sant' Onofrio 4, 00165, Rome, Italy.
  • Bockenhauer D; Regional Paediatric Nephro-Urology Unit, Southampton Children's Hospital, Tremona Road, Southampton, SO16 6YD, UK.
  • Cadnapaphornchai MA; UCL Department of Renal Medicine, UCL Medical School, Rowland Hill Street, London, NW3 2PF, UK.
  • Shi L; Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Foundation Trust, Great Ormond Street, London, WC1N 3JH, UK.
  • Dandurand A; Rocky Mountain Pediatric Kidney Center, Rocky Mountain Hospital for Children at Presbyterian/St. Luke's Medical Center, 2055 High Street, Suite 270, Denver, CO, 80205, USA.
  • Sikes K; Otsuka Pharmaceutical Development & Commercialization, 2440 Research Boulevard, Rockville, MD, 20850, USA.
  • Shoaf SE; Otsuka Pharmaceutical Development & Commercialization, 508 Carnegie Center Drive, Princeton, NJ, 08540, USA.
Eur J Pediatr ; 178(7): 1013-1021, 2019 Jul.
Article en En | MEDLINE | ID: mdl-31053954
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Riñón Poliquístico Autosómico Dominante / Antagonistas de los Receptores de Hormonas Antidiuréticas / Tolvaptán Tipo de estudio: Clinical_trials Límite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Eur J Pediatr Año: 2019 Tipo del documento: Article País de afiliación: Alemania
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Riñón Poliquístico Autosómico Dominante / Antagonistas de los Receptores de Hormonas Antidiuréticas / Tolvaptán Tipo de estudio: Clinical_trials Límite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Eur J Pediatr Año: 2019 Tipo del documento: Article País de afiliación: Alemania